PIPA523105
TLR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA523105-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA523105 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
TLR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLR3
Gene Alias
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100037937, 142980, 7098
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Dot Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O15455, Q99MB1
Gene Symbols
TLR3
Immunogen
A mix of synthetic peptides corresponding to amino acids 135-150, 828-844, and 876-891 of TLR3/CD283 protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: mouse spleen lysate or protein
- TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from drosophila to humans and share structural and functional similarities
- TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes
- TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons
- Further, TLR3 may play a role in host defense against viruses, and the use of alternative polyadenylation sites to generate different length transcripts has been noted for the TLR3 gene
- Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans
- The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition
- TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway
- TLR3 is the only human TLR which does not utilize MyD88 as an adaptor molecule instead utilizing TRIF in a signaling path which results in downstream activation of IRF-3 and NF-kB
- TLR3 activation leads not only to Type I interferon induction but also to other inflammatory cytokines which result in DC maturation
- TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection
- Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.
Compare Similar Items
Show Difference
Antigen: TLR3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLR3
Gene Alias: AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100037937, 142980, 7098
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O15455, Q99MB1
Gene Symbols: TLR3
Immunogen: A mix of synthetic peptides corresponding to amino acids 135-150, 828-844, and 876-891 of TLR3/CD283 protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
TLR3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLR3
Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100037937, 142980, 7098
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Dot Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O15455, Q99MB1
Gene Symbols:
TLR3
Immunogen:
A mix of synthetic peptides corresponding to amino acids 135-150, 828-844, and 876-891 of TLR3/CD283 protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: RGS18
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RGS18
Gene Alias: regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 64214, 64407
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 50% glycerol and 0.025% sodium azide
Gene Accession No.: Q99PG4, Q9NS28
Gene Symbols: RGS18
Immunogen: Within the range of amino acids 30-62 of human RGS18 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RGS18
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RGS18
Gene Alias:
regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1
Host Species:
Rabbit
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
64214, 64407
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 50% glycerol and 0.025% sodium azide
Gene Accession No.:
Q99PG4, Q9NS28
Gene Symbols:
RGS18
Immunogen:
Within the range of amino acids 30-62 of human RGS18 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TLR6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLR6
Gene Alias: CD antigen 286; CD286; TLR6; toll like receptor 6; toll-like receptor 6
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 10333
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: Conc. Not Determined
Formulation: whole serum with 50% glycerol and 0.025% sodium azide
Gene Accession No.: Q9Y2C9
Gene Symbols: TLR6
Immunogen: Within the range of amino acids 25-56 of human TLR6 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TLR6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLR6
Gene Alias:
CD antigen 286; CD286; TLR6; toll like receptor 6; toll-like receptor 6
Host Species:
Rabbit
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
10333
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
Conc. Not Determined
Formulation:
whole serum with 50% glycerol and 0.025% sodium azide
Gene Accession No.:
Q9Y2C9
Gene Symbols:
TLR6
Immunogen:
Within the range of amino acids 25-56 of human TLR6 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: AGR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Agr2
Gene Alias: AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10551, 23795
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O88312, O95994
Gene Symbols: Agr2
Immunogen: Synthetic peptides corresponding to amino acids 55-72 (TQTYEEALYKSKTSNKPL) of human AGR2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AGR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Agr2
Gene Alias:
AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10551, 23795
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O88312, O95994
Gene Symbols:
Agr2
Immunogen:
Synthetic peptides corresponding to amino acids 55-72 (TQTYEEALYKSKTSNKPL) of human AGR2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG