PIPA523349

TLR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523349-Each-of-1 In Stock ₹ 46,159.62

PIPA523349 - Each of 1

₹ 46,159.62

In Stock

Quantity

1

Base Price: ₹ 46,159.62

GST (18%): ₹ 8,308.732

Total Price: ₹ 54,468.352

Antigen

TLR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLR3

Gene Alias

AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

142980, 7098

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O15455, Q99MB1

Gene Symbols

TLR3

Immunogen

A portion of amino acids 750-800 of human TLR3

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from drosophila to humans and share structural and functional similarities
  • TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes
  • TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons
  • Further, TLR3 may play a role in host defense against viruses, and the use of alternative polyadenylation sites to generate different length transcripts has been noted for the TLR3 gene
  • Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans
  • The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition
  • TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway
  • TLR3 is the only human TLR which does not utilize MyD88 as an adaptor molecule instead utilizing TRIF in a signaling path which results in downstream activation of IRF-3 and NF-kB
  • TLR3 activation leads not only to Type I interferon induction but also to other inflammatory cytokines which result in DC maturation
  • TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection
  • Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA523349

--


Antigen:
TLR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
142980, 7098

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O15455, Q99MB1

Gene Symbols:
TLR3

Immunogen:
A portion of amino acids 750-800 of human TLR3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523353

--


Antigen:
Phospho-FGFR1 (Tyr651, Tyr652)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGFR1

Gene Alias:
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2260

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
P11362

Gene Symbols:
FGFR1

Immunogen:
Synthetic peptide corresponding to amino acids (644) RDIHHIDYYKKTTN (657) of human FGFR1, containing phosphorylated tyrosine residues at 651 and 652

Quantity:
20 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523354

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Antigen:
Phospho-beta Catenin (Ser33, Ser37)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1499

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
P35222

Gene Symbols:
CTNNB1

Immunogen:
Synthetic peptide (32 D(S)GIH(S)GATTTAPS 45) of Phospho-Beta-catenin pSer33/Ser37 protein.

Quantity:
20 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523355

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Antigen:
OTUD5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OTUD5

Gene Alias:
AA407879; AI553596; BB114028; deubiquinating enzyme A; deubiquitinating enzyme A; DUBA; DXImx46e; OTU deubiquitinase 5; OTU domain containing 5; OTU domain-containing protein 5; Otud5; Sfc7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
363452, 54644, 55593

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q2YDU3, Q3U2S4, Q96G74

Gene Symbols:
OTUD5

Immunogen:
A portion of amino acids 550-571 of human DUBA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG