PIPA523125

TLR4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523125-Each-of-1 In Stock ₹ 47,528.58

PIPA523125 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

TLR4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLR4

Gene Alias

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21898, 399541, 7099

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O00206, Q68Y56, Q9QUK6

Gene Symbols

TLR4

Immunogen

Synthetic peptide (aa 420-456) of TLR4/CD284 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine

Product Type

Antibody

Isotype

IgG

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Description

  • TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
  • Mammalian cells respond to LPS by activating TLR4
  • TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
  • TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
  • Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
  • TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
  • Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
  • Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA523125

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Antigen:
TLR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21898, 399541, 7099

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O00206, Q68Y56, Q9QUK6

Gene Symbols:
TLR4

Immunogen:
Synthetic peptide (aa 420-456) of TLR4/CD284 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG

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PIPA523128

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Antigen:
DUSP18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DUSP18

Gene Alias:
bK963H5.1; DSP18; dual specificity phosphatase 18; dual specificity protein phosphatase 18; DUSP18; DUSP20; hypothetical protein LOC505912; LMWDSP20; LMW-DSP20; Low molecular weight dual specificity phosphatase 20

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
150290, 505912

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.:
Q5BIP9, Q8NEJ0

Gene Symbols:
DUSP18

Immunogen:
Synthetic peptide (9 PVQFRQPSVSGLSQ 22) of DUSP18 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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PIPA523132

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Antigen:
FOXO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2308

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q12778

Gene Symbols:
FOXO1

Immunogen:
A portion of amino acids 250-300 of human FOXO1A protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA523139

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Antigen:
CYP1B1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cyp1b1

Gene Alias:
aryl hydrocarbon hydroxylase; benz[a]anthracene inducible; CP1B; CYP1B; CYP1B1; Cyp1-b1; CYPIB1; cytochrome P450 1B; cytochrome P450 1B1; cytochrome P450 family 1 subfamily B member 1; cytochrome P450, 1b1, benz[a]anthracene inducible; cytochrome P450, family 1, subfamily B, polypeptide 1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); cytochrome P4501B; cytochrome P450CMEF; Cytochrome P450EF; cytochrome P450RAP; flavoprotein-linked monooxygenase; GLC3A; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P4501B1; P450RAP; xenobiotic monooxygenase; zgc:136223

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1545

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), In vitro Assay, Western Blot

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q16678

Gene Symbols:
Cyp1b1

Immunogen:
A portion of amino acids 400-450 of human CYP1B1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG