PIPA523318

USP13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523318-Each-of-1 In Stock ₹ 44,705.10

PIPA523318 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

USP13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP13

Gene Alias

2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100065844, 100141289, 478640, 72607, 8975

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

E1BMF7, Q5BKP2, Q92995

Gene Symbols

USP13

Immunogen

A portion of amino acids 500-550 of human USP13

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Equine, Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD)
  • Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes
  • Also deubiquitinates USP10, an essential regulator of p53/TP53 stability
  • In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13
  • Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD)
  • Also regulates ERAD through the deubiquitination of UBL4A a component of the BAG6/BAT3 complex
  • Mediates stabilization of SIAH2 independently of deubiquitinase activity: binds ubiquitinated SIAH2 and acts by impairing SIAH2 autoubiquitination
  • Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains
  • In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly
  • Able to cleave ISG15 in vitro; however, additional experiments are required to confirm such data
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA523318

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Antigen:
USP13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP13

Gene Alias:
2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100065844, 100141289, 478640, 72607, 8975

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
E1BMF7, Q5BKP2, Q92995

Gene Symbols:
USP13

Immunogen:
A portion of amino acids 500-550 of human USP13

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Equine, Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523319

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Antigen:
eIF3g

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF3G

Gene Alias:
44kDa; D0Jmb4; eiF3 delta; eIF3 p42; eIF3 p42 {ECO:0000255; eIF3 p44; eIF3 p44 {ECO:0000255; eIF-3 RNA-binding subunit; eIF-3 RNA-binding subunit {ECO:0000255; eIF-3-delta; eIF3-delta; eIF-3-delta {ECO:0000255; EIF3G; eIF3g {ECO:0000255; Eif3p42; EIF3-P42; eIF3-p44; EIF3S4; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255; eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3 subunit G {ECO:0000255; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3, subunit 4 delta; eukaryotic translation

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100055350, 298700, 53356, 612971, 615695, 8666

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O75821, Q3ZC12, Q5RK09, Q9Z1D1

Gene Symbols:
EIF3G

Immunogen:
A portion of amino acids 200-250 of human eIF3G

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Equine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523320

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Antigen:
NALP9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NLRP9

Gene Alias:
CLR19.1; D7Ertd565e; NACHT, leucine rich repeat and PYD containing 9; NACHT, LRR and PYD containing protein 9; NACHT, LRR and PYD containing protein 9a; NACHT, LRR and PYD containing protein 9b; NACHT, LRR and PYD domains-containing protein 9; NACHT, LRR and PYD domains-containing protein 9A; NALP9; Nalp9a; Nalp9b; NALP-theta; NLR family pyrin domain containing 9; NLR family, pyrin domain containing 9; NLR family, pyrin domain containing 9A; NLR family, pyrin domain containing 9B; NLRP9; Nlrp9a; Nlrp9b; NOD6; Nucleotide-binding oligomerization domain protein 6; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 9; PAN12; PYRIN and NACHT-containing protein 12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
233001, 338321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q66X03, Q7RTR0

Gene Symbols:
NLRP9, Nlrp9a

Immunogen:
A portion of amino acids 330-380 of human NALP9

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA523322

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Antigen:
CENTG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Agap2

Gene Alias:
AGAP2; AGAP-2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin gamma1; centaurin, gamma 1; centaurin-gamma-1; CENTG1; cnt-g1; FLJ16430; GGAP2; GTP-binding and GTPase activating protein 2; GTP-binding and GTPase-activating protein 2; KIAA0167; mKIAA0167; nuclear GTPase PIKE; phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; phosphoinositide 3-kinase enhancer; Pike

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116986

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q99490

Gene Symbols:
Agap2

Immunogen:
A portion of amino acids 20-60 of human AGAP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG