PIPA523333

USP7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA523333-Each-of-1 In Stock ₹ 45,560.70

PIPA523333 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

USP7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP7

Gene Alias

2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100057484, 252870, 360471, 395126, 479854, 7874

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

Q4VSI4, Q6A4J8, Q6U7I1, Q93009

Gene Symbols

USP7

Immunogen

A portion of amino acids 30-80 of human USP7 protein

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Chicken, Equine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
  • Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA523333

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Antigen:
USP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100057484, 252870, 360471, 395126, 479854, 7874

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q4VSI4, Q6A4J8, Q6U7I1, Q93009

Gene Symbols:
USP7

Immunogen:
A portion of amino acids 30-80 of human USP7 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Chicken, Equine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523335

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Antigen:
PLD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pld2

Gene Alias:
choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; phospholipase D2; PLD 2; PLD1C; PLD2; Pldc; rPLD2

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
5338

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 50% glycerol and 0.025% sodium azide

Gene Accession No.:
O14939

Gene Symbols:
Pld2

Immunogen:
Within the range amino acids 199-230 of human PLD2 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523341

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Antigen:
REG3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Reg3a

Gene Alias:
AV063448; generating islet-derived, mouse homolog 3 alpha; hepatocarcinoma-intestine-pancreas; hepatointestinal pancreatic protein; HIP; HIP/PAP; human proislet peptide; INGAP; islet of Langerhans regenerating protein 3; Lithostathine 3; pancreatic beta cell growth factor; pancreatitis-associated protein 1; Pancreatitis-associated protein 2; PAP; PAP homologous protein; PAP1; Pap2; PAP-H; PapII; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; REG 3; REG 3a; REG 3alpha; Reg IIIalpha; Reg III-alpha; REG3; REG3 alpha; Reg3a; REG3alpha; REG-3alpha; REG-3-alpha; regeneratin; regenerating family member 3 alpha; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3 alpha; regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein 3-alpha 15 kDa form; Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein III-alpha; regIII; REG-III; RegIII (alpha)

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5068

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q06141

Gene Symbols:
Reg3a

Immunogen:
A portion of amino acids 1-50 of human REG3A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA523345

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Antigen:
ASAP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASAP2

Gene Alias:
6530401G17Rik; AMAP2; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; Asap2; centaurin, beta 3; CENTB3; DDEF2; development and differentiation enhancing factor 2; development and differentiation-enhancing factor 2; Gm1523; Gm592; KIAA0400; PAG3; PAP; Pap-alpha; PAPbeta; Paxillin-associated protein with ARF GAP activity 3; PYK2 C terminus-associated protein; pyk2 C-terminus-associated protein; SHAG1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
211914, 362719, 8853

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O43150, Q7SIG6

Gene Symbols:
ASAP2

Immunogen:
A portion of amino acids 700-750 of human ASAP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Marsupial, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG