PIPA528087
POLR2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528087-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA528087 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
POLR2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR2A
Gene Alias
220kDa; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directeced RNA polymerase II polypeptide A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; N0825; Pol II S2p; POL2; POLR2; Polr2a; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5430
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.72 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P24928
Gene Symbols
POLR2A
Immunogen
Synthetic peptide corresponding to a region within amino acids 1805 and 1899 of Human DNA polymerase IIA
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Recommended positive controls: 293T, A431, H1299, HepG2, Raji
- Predicted reactivity: Mouse (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- DNA-directed RNA polymerase II subunit RPB1 (POLR1A) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- POLR1A is the largest subunit and is a catalytic component of RNA polymerase II which synthesizes mRNA precurors and many functional non-coding RNAs
- It also forms the polymerase active center together with the second largest subunit
- Pol II is the central component of the basal RNA polymerase II transcription machinery
- It is composed of mobile elements that move relative to each other
- RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft, and the jaws that are though to grab the incoming DNA template
- At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II
- A bridging helix emanates from RPB1 and crosses the cleft near the catalytic stie and is through to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition
- During transcription elongation, Pol II moves on the template as the transcript elongates
- Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II's largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination, and mRNA processing
- Regulation of gene expression levels depends on the balance between methylation and acetylation levelts of the CTD-lysines.
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Antigen: POLR2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directeced RNA polymerase II polypeptide A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; N0825; Pol II S2p; POL2; POLR2; Polr2a; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5430
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.72 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P24928
Gene Symbols: POLR2A
Immunogen: Synthetic peptide corresponding to a region within amino acids 1805 and 1899 of Human DNA polymerase IIA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
POLR2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directeced RNA polymerase II polypeptide A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; N0825; Pol II S2p; POL2; POLR2; Polr2a; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5430
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.72 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P24928
Gene Symbols:
POLR2A
Immunogen:
Synthetic peptide corresponding to a region within amino acids 1805 and 1899 of Human DNA polymerase IIA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Stathmin 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stmn1
Gene Alias: 19k; C1orf215; I79_017954; Lag; LAP18; leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; P18; P19; phosphoprotein 19; phosphoprotein p19; Pig; pp17; Pp18; Pp19; Pr22; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; SMN; Stathmin; stathmin 1; stathmin 1 variant; stathmin 1/oncoprotein 18; Stmn1; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16765, 29332, 3925
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P13668, P16949, P54227
Gene Symbols: Stmn1
Immunogen: Synthetic peptide corresponding to a region within amino acids 85 and 149 of Human Stathmin 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Stathmin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stmn1
Gene Alias:
19k; C1orf215; I79_017954; Lag; LAP18; leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; P18; P19; phosphoprotein 19; phosphoprotein p19; Pig; pp17; Pp18; Pp19; Pr22; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; SMN; Stathmin; stathmin 1; stathmin 1 variant; stathmin 1/oncoprotein 18; Stmn1; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16765, 29332, 3925
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P13668, P16949, P54227
Gene Symbols:
Stmn1
Immunogen:
Synthetic peptide corresponding to a region within amino acids 85 and 149 of Human Stathmin 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HPK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: EC 2.7.11.1; Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK; HPK1; MAP4K1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mHPK1; mitogen activated protein kinase kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase kinase 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human MAP4K1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HPK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
EC 2.7.11.1; Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK; HPK1; MAP4K1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mHPK1; mitogen activated protein kinase kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase kinase 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human MAP4K1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DUSP10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DUSP10
Gene Alias: 2610306G15Rik; AI158871; dual specificity phosphatase 10; dual specificity phosphatase MKP-5; dual specificity protein phosphatase 10; Dusp10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; Mkp5; MKP-5; serine/threonine specific protein phosphatase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11221
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9Y6W6
Gene Symbols: DUSP10
Immunogen: Synthetic peptide corresponding to a region within amino acids 419 and 482 of Human DUSP10
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DUSP10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DUSP10
Gene Alias:
2610306G15Rik; AI158871; dual specificity phosphatase 10; dual specificity phosphatase MKP-5; dual specificity protein phosphatase 10; Dusp10; MAP kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; Mkp5; MKP-5; serine/threonine specific protein phosphatase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11221
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9Y6W6
Gene Symbols:
DUSP10
Immunogen:
Synthetic peptide corresponding to a region within amino acids 419 and 482 of Human DUSP10
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG