PIPA529389

ARC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529389-Each-of-1 In Stock ₹ 44,277.30

PIPA529389 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

ARC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOL3

Gene Alias

activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8996

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.64 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O60936

Gene Symbols

NOL3

Immunogen

Synthetic peptide corresponding to a region within amino acids 138 and 192 of Human NOL3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms
  • Isoform 1 is involved in RNA splicing
  • Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death
  • ARC inhibits extrinsic apoptotic pathways two different ways
  • The first is by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly
  • The second way is by interacting with CASP8 in a mitochondria localization-and phosphorylation-dependent manner, which in turn limits the amount of soluble CASP8 avaliable for DISC-mediated activation
  • ARC also inhibits intrinsic apoptotic pathways in response to a wide range of stresses through interactions with BAX
  • This results in BAX inactivation and prevents mitochondrial dysfunction and release of pro-apoptotic factors
  • Mutations affecting the gene can results in myoclonus, familiam cortical.

Compare Similar Items

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Img

Thermo Scientific

PIPA529389

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Antigen:
ARC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOL3

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8996

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.64 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O60936

Gene Symbols:
NOL3

Immunogen:
Synthetic peptide corresponding to a region within amino acids 138 and 192 of Human NOL3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529390

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Antigen:
SFRP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SFRP2

Gene Alias:
AI851596; FKSG12; FRP 2; FRP2; FRP-2; MGC128911; MGC153618; MGC53344; Protein SDF5; SARP 1; SARP1; SARP-1; SDF 5; Sdf5; SDF-5; secreted apoptosis related protein 1; secreted apoptosis-related protein 1; secreted frizzled related protein 2; secreted frizzled-related protein 2; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; sFRP 2; SFRP2; sFRP-2; Sfrp2 protein; stromal cell derived factor 5; testicular tissue protein Li 170; UNQ361/PRO697

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6423

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.12 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q96HF1

Gene Symbols:
SFRP2

Immunogen:
Synthetic peptide corresponding to a region within amino acids 231 and 295 of Human FRP 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529392

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Antigen:
ATOH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atoh1

Gene Alias:
ATH1; Atoh1; atonal bHLH transcription factor 1; atonal homolog 1; atonal homolog 1 (Drosophila); atonal homolog bHLH transcription factor 1; BHLHA14; Class A basic helix-loop-helix protein 14; H MATH-1; Hath1; Helix-loop-helix protein hATH-1; helix-loop-helix protein mATH-1; Math1; MATH-1; Protein atonal homolog 1; RGD1565171

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11921, 474, 500156

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.05 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P48985, Q92858

Gene Symbols:
Atoh1

Immunogen:
Synthetic peptide corresponding to a region within amino acids 285 and 354 of Human MATH1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529393

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Antigen:
CDK5RAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK5RAP1

Gene Alias:
2310066P17Rik; C20orf34; C42; CDK5 activator-binding protein C42; CDK5 regulatory subunit associated protein 1; CDK5 regulatory subunit-associated protein 1; CDK5 regulatory subunit-associated protein 1-like protein; CDK5RAP1; CDK5RAP1.3; CDK5RAP1.4; CGI-05; HSPC167; mitochondrial tRNA methylthiotransferase CDK5RAP1; CDK5 regulatory subunit-associated protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
252827, 51654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96SZ6, Q9JLH6

Gene Symbols:
CDK5RAP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 305 and 590 of Human CDK5RAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG