PIPA529861

ARC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA529861-Each-of-1 In Stock ₹ 44,619.54

PIPA529861 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

ARC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOL3

Gene Alias

activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

78688, 85383, 8996

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

O60936, Q62881, Q9D1X0

Gene Symbols

NOL3

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 197 of Human NOL3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLa
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ARC (also known as NOL3 - Nucleolar protein 3) has two isoforms
  • Isoform 1 is involved in RNA splicing
  • Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death
  • ARC inhibits extrinsic apoptotic pathways two different ways
  • The first is by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly
  • The second way is by interacting with CASP8 in a mitochondria localization-and phosphorylation-dependent manner, which in turn limits the amount of soluble CASP8 avaliable for DISC-mediated activation
  • ARC also inhibits intrinsic apoptotic pathways in response to a wide range of stresses through interactions with BAX
  • This results in BAX inactivation and prevents mitochondrial dysfunction and release of pro-apoptotic factors
  • Mutations affecting the gene can results in myoclonus, familiam cortical.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA529861

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Antigen:
ARC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOL3

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Apoptosis repressor with CARD; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; B430311C09Rik; C86064; FCM; hArc; KIAA0278; mArc; Muscle-enriched cytoplasmic protein; MYC; MYP; Nol3; NOP; Nop 30; Nop30; Nucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); nucleolar protein of 30 kDa; rg3.1; RGD:62037}

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
78688, 85383, 8996

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.3 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O60936, Q62881, Q9D1X0

Gene Symbols:
NOL3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 197 of Human NOL3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA529862

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Antigen:
AIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aip

Gene Alias:
AA408703; AH receptor-interacting protein; AIP; ARA9; aryl hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; AW476050; D19Bwg1412e; FKBP16; FKBP37; HBV X-associated protein 2; HBV-X associated protein; immunophilin homolog ARA9; Immunophilin XAP2; SMTPHN; XAP2; XAP-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11632, 9049

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.01 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O00170, O08915

Gene Symbols:
Aip

Immunogen:
Recombinant fragment contain a sequence corresponding to a region within amino acids 37 and 294 of ARA9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529865

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Antigen:
NR1D1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR1D1

Gene Alias:
A530070C09Rik; BD73; Ear1; ear-1; EAR-1R; HREV; NR1D1; nuclear receptor protein; nuclear receptor Rev-ErbA-alpha; nuclear receptor subfamily 1 group D member 1; nuclear receptor subfamily 1, group D, member 1; orphan nuclear receptor; R75201; rev-erb alpha; Rev-erba; rev-erbA alpha; rev-erbA(alpha); Reverbaalpha; Rev-ErbAalpha; rev-erbA-alpha; Rev-ErbA-alpha protein; REV-ERBalpha; RVR; THRA1; THRAL; V-erbA-related protein 1; V-erbA-related protein EAR-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
217166, 9572

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.31 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P20393, Q3UV55

Gene Symbols:
NR1D1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 246 and 558 of Human NR1D1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529868

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Antigen:
LXR alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10062, 22259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q13133, Q9Z0Y9

Gene Symbols:
NR1H3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 243 of Human LXR alpha

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG