PIPA529610

Tau Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529610-Each-of-1 In Stock ₹ 47,699.70

PIPA529610 - Each of 1

₹ 47,699.70

In Stock

Quantity

1

Base Price: ₹ 47,699.70

GST (18%): ₹ 8,585.946

Total Price: ₹ 56,285.646

Antigen

Tau

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17762, 29477, 4137

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

0.12 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P10636, P10637, P19332

Gene Symbols

MAPT

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 1 and 189 of Human Tau

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: mouse brain, Rat brain
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA529610

--


Antigen:
Tau

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.12 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 189 of Human Tau

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529611

--


Antigen:
MyD88

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYD88

Gene Alias:
mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17874, 4615

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.93 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P22366, Q99836

Gene Symbols:
MYD88

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 260 of Human MYD88

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529612

--


Antigen:
NME1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NME1

Gene Alias:
AL024257; AWD; expressed in non-metastatic cells 1; expressed in non-metastatic cells 1 protein; expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase); expressed in non-metastatic cells 1, protein; expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase); GAAD; Granzyme A activated DNase (GAAD); Granzyme A-activated DNase; GZMA activated DNase; included; metastasis inhibition factor NM23; NB; NBR-A; NBR-B; NBS; NDK A; NDK A 1; NDK A 2; NDK NBR-A; NDK NBR-B; NDKA; NDP kinase A; NDP kinase A 1; NDP kinase A 2; NDP kinase beta; NDP kinase NBR-A; NDPKA; NDPK-A; NM23; NM23A; NM23-C1; NM23-H1; NM23H1B; nm23-M1; NME/NM23 nucleoside diphosphate kinase 1; Nme1; NME1-1; NME1-NME2 spliced read-through transcript; non-metastatic cells 1, protein (NM23A) expressed in; nucleoside diphosphate kinase A; nucleoside diphosphate kinase A 1; nucleoside diphosphate kinase A 2; nucleoside diphosphate kinase NBR-B; nucleoside-diphosphate kinase 1; nuc

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18102, 4830

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P15531, P15532

Gene Symbols:
NME1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 152 of Human nm23-H1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA529613

--


Antigen:
PI3K p85 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIK3R1

Gene Alias:
AGM7; GRB1; IMD36; p50alpha; p55alpha; p55-GAMMA; p55PIK; p85; p85alpha; p85-ALPHA; phosphatidylinositol 3-kinase; phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50); Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphoinositide-3-kinase regulatory subunit; phosphoinositide-3-kinase regulatory subunit 1; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha); phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); PI3K; PI3K regulatory subunit alph

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5295

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P27986

Gene Symbols:
PIK3R1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 538 and 724 of Human PI3 kinase p85 alpha

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG