PIPA529693

AIF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529693-Each-of-1 In Stock ₹ 49,410.90

PIPA529693 - Each of 1

₹ 49,410.90

In Stock

Quantity

1

Base Price: ₹ 49,410.90

GST (18%): ₹ 8,893.962

Total Price: ₹ 58,304.862

Antigen

AIF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26926, 83533, 9131

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O95831, Q9JM53, Q9Z0X1

Gene Symbols

AIFM1

Immunogen

Recombinant fragment corresponding to a region within amino acids 82 and 330 of Human AIF

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver, rat liver
  • Predicted reactivity: Mouse (95%), Rat (96%), Zebrafish (80%), Pig (97%), Chicken (84%), Rhesus Monkey (99%), Bovine (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

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Thermo Scientific

PIPA529693

--


Antigen:
AIF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AG1; AGR1; Aif; AIFM1; AIFsh2; apoptosis inducing factor mitochondria associated 1; apoptosis inducing factor, mitochondria associated 1; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor, mitochondrion-associated 1; apoptosis-inducing factor, mitochondrion-associated, 1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; ER protein 18; ER protein 19; ERP18; ERP19; hAG-1; harlequin; Hq; hTLP19; MGC111425; mitochondrial apoptosis-inducing factor 1; NADMR; NAMSD; pcd8; PDCD8; PDIA16; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8; RP3-438D16.2; striatal apoptosis-inducing factor; testicular secretory protein Li 4; TLP19; UNQ713/PRO1376

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26926, 83533, 9131

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95831, Q9JM53, Q9Z0X1

Gene Symbols:
AIFM1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 82 and 330 of Human AIF

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA529694

--


Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11793, 9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Proximity Ligation Assay, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99J83, Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Recombinant fragment corresponding to a region within amino acids 64 and 275 of Human APG5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529696

--


Antigen:
AKT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT3

Gene Alias:
AI851531; AKT serine/threonine kinase 3; Akt3; AKT3 kinase; akt3a; D930002M15Rik; DKFZP434N0250; MPPH; MPPH2; Nmf350; PKB gamma; PKBG; PKB-GAMMA; PRKBG; Protein kinase Akt-3; protein kinase B gamma; protein kinase B, gamma; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; si:ch211-221n23.2; STK-2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10000, 23797

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.15 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9WUA6, Q9Y243

Gene Symbols:
AKT3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 164 of Human AKT3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529698

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Antigen:
RACGAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RACGAP1

Gene Alias:
AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29127

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9H0H5

Gene Symbols:
RACGAP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 395 and 632 of Human RACGAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG