PIPA529694

ATG5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529694-Each-of-1 In Stock ₹ 45,817.38

PIPA529694 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

ATG5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11793, 9474

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Proximity Ligation Assay, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q99J83, Q9H1Y0

Gene Symbols

Atg5

Immunogen

Recombinant fragment corresponding to a region within amino acids 64 and 275 of Human APG5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: NT2D1, PC-3, HeLa, HeLa (chloroquine treatment for 24hr)
  • Predicted reactivity: Mouse (95%), Xenopus laevis (81%), Chicken (87%), Bovine (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

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Thermo Scientific

PIPA529694

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Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11793, 9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Proximity Ligation Assay, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q99J83, Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Recombinant fragment corresponding to a region within amino acids 64 and 275 of Human APG5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529696

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Antigen:
AKT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKT3

Gene Alias:
AI851531; AKT serine/threonine kinase 3; Akt3; AKT3 kinase; akt3a; D930002M15Rik; DKFZP434N0250; MPPH; MPPH2; Nmf350; PKB gamma; PKBG; PKB-GAMMA; PRKBG; Protein kinase Akt-3; protein kinase B gamma; protein kinase B, gamma; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; si:ch211-221n23.2; STK-2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); v-akt murine thymoma viral oncogene homolog 3a; v-akt murine thymoma viral oncogene-like 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10000, 23797

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.15 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9WUA6, Q9Y243

Gene Symbols:
AKT3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 164 of Human AKT3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA529698

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Antigen:
RACGAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RACGAP1

Gene Alias:
AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29127

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9H0H5

Gene Symbols:
RACGAP1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 395 and 632 of Human RACGAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529701

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Antigen:
WWOX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Wwox

Gene Alias:
5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292041, 51741, 80707

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q91WL8, Q9NZC7

Gene Symbols:
Wwox

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 186 of Human WWOX

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG