PIPA529966

ALAS1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529966-Each-of-1 In Stock ₹ 45,218.46

PIPA529966 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

ALAS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.71 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

Recombinant fragment corresponding to a region within amino acids 62 and 304 of Human ALAS-H

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: Raji
  • Predicted reactivity: Mouse (87%), Rat (85%), Bovine (85%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5' phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

Compare Similar Items

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Thermo Scientific

PIPA529966

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Antigen:
ALAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.71 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 62 and 304 of Human ALAS-H

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529967

--


Antigen:
SLC25A6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slc25a6

Gene Alias:
4930433D19Rik; 4933433F13Rik; AAC3; adenine nucleotide translocator 2; adenine nucleotide translocator 3; adenine nucleotide translocator 3 (liver); ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 3; ADP/ATP translocase 3, N-terminally processed; ADP/ATP translocator of liver; ANT; ANT 2; ANT 3; ANT3; ANT3Y; AW557176; CDABP0051; D6Bwg0781e; mitochondrial ADP/ATP carrier protein; mitochondrial S-adenosylmethionine transporter; mitochondrial solute carrier family 25 member 6; S-adenosylmethionine mitochondrial carrier protein; Samc; si:dkey-21o13.4; Slc25a26; slc25a6; solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; solute carrier family 25 member 26; Solute carrier family 25 member 6; solute carrier family 25, member A6; translocase; wu:fj78b08

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
293

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P12236

Gene Symbols:
Slc25a6

Immunogen:
Recombinant fragment corresponding to a region within amino acids 57 and 298 of Human SLC25A6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA529968

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Antigen:
Annexin A11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANXA11

Gene Alias:
56 kDa autoantigen; A830099O17Rik; annexin; annexin A11; Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50); annexin XI; Annexin-11; ANX11; Anxa11; autoantigen; autoantigen, 56-kD; calcyclin-associated annexin 50; Calcyclin-associated annexin-50; CAP50; CAP-50; OTTHUMP00000019957; OTTHUMP00000019958; RP11-369J21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
311

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.35 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P50995

Gene Symbols:
ANXA11

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 299 of Human Annexin A11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA529970

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Antigen:
ARF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARF3

Gene Alias:
35-beta calcimedin; 5430400P17Rik; Ac1-253; ADP ribosylation factor 3; ADP-ribosylation factor 3; AI854770; Annexin A4; Annexin IV; Annexin-4; ANX4; ANXA4; Arf3; Chromobindin-4; Endonexin I; Lipocortin IV; Liver regeneration-related protein LRRG202; P32.5; PAP-II; PP4-X; small GTP binding protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11842, 377

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.31 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P61204, P61205

Gene Symbols:
ARF3

Immunogen:
Recombinant protein fragment corresponding to a region within amino acids 1 and 129 of Human ARF3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG