PIPA532267

Arginase 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532267-Each-of-1 In Stock ₹ 47,528.58

PIPA532267 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Arginase 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARG1

Gene Alias

AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11846, 29221, 383

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.046 mg/mL

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.

P05089, P07824, Q61176

Gene Symbols

ARG1

Immunogen

Synthetic peptide derived from the N-terminus of human arginase-1 protein.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
  • A suggested positive control is hepatocellular carcinoma
  • Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
  • The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
  • By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
  • In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
  • In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
  • In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
  • Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
  • Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA532267

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Antigen:
Arginase 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARG1

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11846, 29221, 383

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.046 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P05089, P07824, Q61176

Gene Symbols:
ARG1

Immunogen:
Synthetic peptide derived from the N-terminus of human arginase-1 protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA532282

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Antigen:
E-cadherin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDH1

Gene Alias:
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
999

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.03 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P12830

Gene Symbols:
CDH1

Immunogen:
Recombinant protein encoding human cadherin-E 600-707aa

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA532295

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Antigen:
gamma Catenin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JUP

Gene Alias:
ARVD12; catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; cb80; cell-adhesion protein plakoglobin; Ctnng; D930025P04Rik; danPG; Desmoplakin III; desmoplakin-3; desmosomal protein; DP3; DPIII; fb11b06; gama-catenin; gamma-catenin; gamma-catenin (plakoglobin); junction plakoglobin; junction plakoglobin a; Jup; jup protein; jupa; OTTHUMP00000164735; PDGB; PG; PKGB; plakoglobin; wu:fb11b06

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3728

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
PBS with 1% BSA and <0.1% sodium azide; pH 7.6

Gene Accession No.:
P14923

Gene Symbols:
JUP

Immunogen:
Synthetic peptide derived from the C-terminus of human catenin-gamma protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA532297

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Antigen:
Caveolin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAV1

Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
857

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
Q03135

Gene Symbols:
CAV1

Immunogen:
Synthetic peptide from N-terminus of human caveolin-1.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG