PIPA532670
BACE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532670-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA532670 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
BACE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE1
Gene Alias
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100071137, 100135485, 100343442, 100511707, 100762079, 23621, 23821, 29392, 614333
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P56817, P56818, P56819, Q1KLR6, Q2HJ40
Gene Symbols
BACE1
Immunogen
Synthetic 15 amino acid peptide from internal region of human BACE1.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Bat, Bovine, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Guinea pig (100%); Platypus (87%); Xenopus, Pufferfish, Zebrafish, Stickleback (80%)
- For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
- BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff
- APP is first cleaved by b-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99)
- The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide, which is deposited in the brains of all sufferers of Alzheimer's disease
- The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)
- bACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
Compare Similar Items
Show Difference
Antigen: BACE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100071137, 100135485, 100343442, 100511707, 100762079, 23621, 23821, 29392, 614333
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P56817, P56818, P56819, Q1KLR6, Q2HJ40
Gene Symbols: BACE1
Immunogen: Synthetic 15 amino acid peptide from internal region of human BACE1.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Bat, Bovine, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BACE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100071137, 100135485, 100343442, 100511707, 100762079, 23621, 23821, 29392, 614333
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P56817, P56818, P56819, Q1KLR6, Q2HJ40
Gene Symbols:
BACE1
Immunogen:
Synthetic 15 amino acid peptide from internal region of human BACE1.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Bat, Bovine, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BACE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23621
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P56817
Gene Symbols: BACE1
Immunogen: Synthetic 18 amino acid peptide near the C-terminus of human BACE1
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
BACE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23621
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P56817
Gene Symbols:
BACE1
Immunogen:
Synthetic 18 amino acid peptide near the C-terminus of human BACE1
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: BAI1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADGRB1
Gene Alias: ADGRB1; Adhesion G protein-coupled receptor B1; B830018M07Rik; Bai1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF; mKIAA4089; R75078; Vasculostatin-120; Vasculostatin-40; Vstat120; Vstat40; Vstat-40
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 524070, 575
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 0.7 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: O14514
Gene Symbols: ADGRB1
Immunogen: Synthetic 18 amino acid peptide from N-terminus of human BAI1.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
BAI1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADGRB1
Gene Alias:
ADGRB1; Adhesion G protein-coupled receptor B1; B830018M07Rik; Bai1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF; mKIAA4089; R75078; Vasculostatin-120; Vasculostatin-40; Vstat120; Vstat40; Vstat-40
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
524070, 575
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
0.7 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
O14514
Gene Symbols:
ADGRB1
Immunogen:
Synthetic 18 amino acid peptide from N-terminus of human BAI1.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: Bombesin Receptor 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRS3
Gene Alias: BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 680
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P32247
Gene Symbols: BRS3
Immunogen: Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human BRS3.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Bombesin Receptor 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRS3
Gene Alias:
BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
680
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P32247
Gene Symbols:
BRS3
Immunogen:
Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human BRS3.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG