PIPA532672
BACE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532672-Each-of-1 | In Stock | ₹ 44,790.66 |
PIPA532672 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,790.66
GST (18%): ₹ 8,062.319
Total Price: ₹ 52,852.979
Antigen
BACE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BACE1
Gene Alias
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23621
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P56817
Gene Symbols
BACE1
Immunogen
Synthetic 18 amino acid peptide near the C-terminus of human BACE1
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Guinea pig (94%); Opossum (89%); Turkey, Chicken, Platypus (83%)
- For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
- BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff
- APP is first cleaved by b-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99)
- The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide, which is deposited in the brains of all sufferers of Alzheimer's disease
- The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)
- bACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
Compare Similar Items
Show Difference
Antigen: BACE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23621
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P56817
Gene Symbols: BACE1
Immunogen: Synthetic 18 amino acid peptide near the C-terminus of human BACE1
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
BACE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23621
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P56817
Gene Symbols:
BACE1
Immunogen:
Synthetic 18 amino acid peptide near the C-terminus of human BACE1
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: BAI1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADGRB1
Gene Alias: ADGRB1; Adhesion G protein-coupled receptor B1; B830018M07Rik; Bai1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF; mKIAA4089; R75078; Vasculostatin-120; Vasculostatin-40; Vstat120; Vstat40; Vstat-40
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 524070, 575
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 0.7 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: O14514
Gene Symbols: ADGRB1
Immunogen: Synthetic 18 amino acid peptide from N-terminus of human BAI1.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
BAI1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADGRB1
Gene Alias:
ADGRB1; Adhesion G protein-coupled receptor B1; B830018M07Rik; Bai1; brain-specific angiogenesis inhibitor 1; FLJ41988; GDAIF; mKIAA4089; R75078; Vasculostatin-120; Vasculostatin-40; Vstat120; Vstat40; Vstat-40
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
524070, 575
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
0.7 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
O14514
Gene Symbols:
ADGRB1
Immunogen:
Synthetic 18 amino acid peptide from N-terminus of human BAI1.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: Bombesin Receptor 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRS3
Gene Alias: BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 680
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P32247
Gene Symbols: BRS3
Immunogen: Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human BRS3.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Bombesin Receptor 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRS3
Gene Alias:
BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
680
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P32247
Gene Symbols:
BRS3
Immunogen:
Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human BRS3.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Bombesin Receptor 3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRS3
Gene Alias: BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100054718, 100763382, 12209, 260319, 539011, 613002, 680
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: O54798, P32247, Q8K418
Gene Symbols: BRS3
Immunogen: Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human BRS3.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Equine, Hamster, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Bombesin Receptor 3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRS3
Gene Alias:
BB3; BB3R; bombesin like receptor 3; bombesin receptor subtype 3; bombesin receptor subtype-3; bombesin-like receptor 3; BRS 3; BRS3; BRS-3; G-protein coupled receptor; RP1-196E23.3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100054718, 100763382, 12209, 260319, 539011, 613002, 680
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
O54798, P32247, Q8K418
Gene Symbols:
BRS3
Immunogen:
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human BRS3.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Equine, Hamster, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG