PIPA532778

Connexin 43 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532778-Each-of-1 In Stock ₹ 44,790.66

PIPA532778 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

Connexin 43

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GJA1

Gene Alias

alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100008935, 100379273, 100518636, 100689077, 14609, 24392, 2697, 281193

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.2 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P08050, P17302, P18246, P23242, Q29101, Q6TYA7

Gene Symbols

GJA1

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human GJA1 / Connexin 43.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Elephant, Panda, Rabbit, Pig, Opossum, Guinea pig (100%); Bat, Horse, Chicken, Lizard, Xenopus (94%); Trout, Salmon (88%); Zebrafish, Sea anemone, Nematode (81%)
  • For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
  • After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
  • Connexin 43 (Cx43) is a member of the gap junction protein family
  • Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels
  • Clusters of these channels assemble to make gap junctions
  • Gap junction communication is important in development and regulation of cell growth
  • Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions
  • Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication
  • Src can interact with and phosphorylate Cx43 to alter gap junction communication
  • GFAP are membrane-spanning proteins that facilitate the transfer of ions and small molecules between cells
  • According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta
  • Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development
  • Connexin 43 is also targeted by several protein kinases that regulate myocardial cell-cell coupling
  • A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5
  • Mutations in the GFAP gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy, oculodentodigital dysplasia and heart malformations
  • Alternatively spliced transcript variants of GFAP have been found.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA532778

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Antigen:
Connexin 43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJA1

Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100008935, 100379273, 100518636, 100689077, 14609, 24392, 2697, 281193

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P08050, P17302, P18246, P23242, Q29101, Q6TYA7

Gene Symbols:
GJA1

Immunogen:
Synthetic 16 amino acid peptide from C-terminus of human GJA1 / Connexin 43.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA532779

--


Antigen:
GLG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLG1

Gene Alias:
AI593353; AW537898; CFR; CFR1; CFR-1; Cysteine-rich fibroblast growth factor receptor; E-selectin ligand 1; ESL1; ESL-1; Glg1; Golgi apparatus protein 1; golgi glycoprotein 1; golgi sialoglycoprotein MG-160; MG160; MG-160; selectin, endothelial cell, ligand; Selel

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100055066, 100340907, 100622584, 100689240, 100716554, 20340, 2734, 281196, 29476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q61543, Q62638, Q92896, Q9Z1E9

Gene Symbols:
GLG1

Immunogen:
Synthetic 18 amino acid peptide from internal region of human GLG1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bat, Bovine, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA532780

--


Antigen:
GLG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLG1

Gene Alias:
AI593353; AW537898; CFR; CFR1; CFR-1; Cysteine-rich fibroblast growth factor receptor; E-selectin ligand 1; ESL1; ESL-1; Glg1; Golgi apparatus protein 1; golgi glycoprotein 1; golgi sialoglycoprotein MG-160; MG160; MG-160; selectin, endothelial cell, ligand; Selel

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100055066, 100340907, 100689240, 20340, 2734, 281196, 29476, 396492, 479654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q02391, Q61543, Q62638, Q92896, Q9Z1E9

Gene Symbols:
GLG1

Immunogen:
Synthetic 18 amino acid peptide from internal region of human GLG1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA532781

--


Antigen:
GLP2R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLP2R

Gene Alias:
9530092J08Rik; G protein-coupled receptor GLP2R; GLP-2; Glp2 receptor; GLP-2 receptor; GLP2R; GLP-2R; GLP-2-R; glucagon like peptide 2 receptor; glucagon-like peptide 2 receptor; glucagon-like peptide-2 receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9340

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
O95838

Gene Symbols:
GLP2R

Immunogen:
Synthetic 16 amino acid peptide from internal region of human GLP2R.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG