PIPA533925

MC4R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533925-Each-of-1 In Stock ₹ 44,705.10

PIPA533925 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MC4R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MC4R

Gene Alias

MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100050469, 4160

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P32245

Gene Symbols

MC4R

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human MC4 Receptor.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Equine, Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Tamarin, Horse (100%)
  • Expression of MC4R has been reported in brain
  • Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA533925

--


Antigen:
MC4R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC4R

Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100050469, 4160

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P32245

Gene Symbols:
MC4R

Immunogen:
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human MC4 Receptor.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Equine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533926

--


Antigen:
MC4R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC4R

Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100147707, 100355375, 4160

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P32245

Gene Symbols:
MC4R

Immunogen:
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human MC4 Receptor.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Ovine, Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533928

--


Antigen:
MC5R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC5R

Gene Alias:
H MC2; MC2; MC-2; MC5; MC5 receptor; MC5R; MC5-R; melanocortin 5 receptor; melanocortin receptor 5; melanocortin-5 receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4161

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P33032

Gene Symbols:
MC5R

Immunogen:
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human MC5 Receptor.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA533931

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Antigen:
MCHR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mchr1

Gene Alias:
AW049955; G protein coupled receptor 24; G protein-coupled receptor 24; GPCR24; GPR24; Gpr24-9 protein coupled receptor; G-protein coupled receptor 24; MCH 1 receptor; MCH receptor 1; MCH1; Mch1r; MCH-1R; MCHR; MCHR1; MCH-R1; MCHR-1; melanin concentrating hormone receptor 1; melanin-concentrating hormone receptor 1; SLC1; SLC-1; Somatostatin receptor-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2847

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q99705

Gene Symbols:
Mchr1

Immunogen:
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human MCHR1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG