PIPA533926

MC4R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533926-Each-of-1 In Stock ₹ 44,705.10

PIPA533926 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MC4R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MC4R

Gene Alias

MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100147707, 100355375, 4160

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P32245

Gene Symbols

MC4R

Immunogen

Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human MC4 Receptor.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Ovine, Rabbit

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Tamarin, Sheep, Rabbit (100%)
  • Expression of MC4R has been reported in brain
  • Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

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Img

Thermo Scientific

PIPA533926

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Antigen:
MC4R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC4R

Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100147707, 100355375, 4160

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P32245

Gene Symbols:
MC4R

Immunogen:
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human MC4 Receptor.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Ovine, Rabbit

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533928

--


Antigen:
MC5R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC5R

Gene Alias:
H MC2; MC2; MC-2; MC5; MC5 receptor; MC5R; MC5-R; melanocortin 5 receptor; melanocortin receptor 5; melanocortin-5 receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4161

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P33032

Gene Symbols:
MC5R

Immunogen:
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human MC5 Receptor.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533931

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Antigen:
MCHR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mchr1

Gene Alias:
AW049955; G protein coupled receptor 24; G protein-coupled receptor 24; GPCR24; GPR24; Gpr24-9 protein coupled receptor; G-protein coupled receptor 24; MCH 1 receptor; MCH receptor 1; MCH1; Mch1r; MCH-1R; MCHR; MCHR1; MCH-R1; MCHR-1; melanin concentrating hormone receptor 1; melanin-concentrating hormone receptor 1; SLC1; SLC-1; Somatostatin receptor-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2847

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q99705

Gene Symbols:
Mchr1

Immunogen:
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human MCHR1.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA533936

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Antigen:
MINK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MINK1

Gene Alias:
B55; FLJ18426; FLJ38123; FLJ94103; GCK family kinase MiNK; hMINK; hMINKbeta; ISK; JLNS; JLNS2; LQT2/5; LQT5; Map4k6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MGC33114; MINK; Mink 1; Mink 2; MINK1; misshapen like kinase 1; misshapen/NIK-related kinase; Misshapen/NIKs-related kinase; misshapen-like kinase 1; misshapen-like kinase 1 (zebrafish); mitogen-activated protein kinase kinase kinase kinase 6; Yeast Sps1/Ste20-related kinase 2; Ysk2; ZC3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100515409, 303259, 50488, 50932, 519558

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
F1LP90, Q8N4C8, Q9JM52

Gene Symbols:
MINK1

Immunogen:
Synthetic 18 amino acid peptide from internal region of human MINK1 / MAP4K6.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG