PIPA534709

Bestrophin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534709-Each-of-1 In Stock ₹ 44,705.10

PIPA534709 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Bestrophin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BEST1

Gene Alias

ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7439

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O76090

Gene Symbols

BEST1

Immunogen

Recombinant fragment corresponding to a region within amino acids 194 and 564 of Bestrophin 1 (Uniprot ID#O76090)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: NT2D1, PC-3, SK-N-SH
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The retinal pigment epithelium (RPE) and choroid represent a differentiated system of the eye that sustains normal retinal health and function
  • Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision
  • The lipofuscin-like material in the macular area appears as a yellow mass like the yolk of an egg that later becomes darker and irregular in color, a process known as &quotescrambling the egg&quote
  • Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells
  • Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium
  • Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current
  • The human Bestrophin gene encodes a 585 amino acid protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA534709

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Antigen:
Bestrophin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BEST1

Gene Alias:
ARB; BEST; BEST 1; Best disease; best macular dystrophy; BEST1; Best1V1Delta2; bestrophin; bestrophin 1; Bestrophin1; Bestrophin-1; BMD; Bmd1; LOW QUALITY PROTEIN: bestrophin-1; mBest1; RP50; TU15B; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog; vitelliform macular dystrophy protein 2; Vitelliform macular dystrophy protein 2 homolog; VMD 2; Vmd2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7439

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O76090

Gene Symbols:
BEST1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 194 and 564 of Bestrophin 1 (Uniprot ID#O76090)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534710

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Antigen:
PKC epsilon

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCE

Gene Alias:
5830406C15Rik; MGC125656; MGC125657; nPKC-epsilon; PKC e; PKC[e]; Pkce; Pkcea; PKCepsilon; PRKCE; PRKCH; protein kinase C; protein kinase C epsilon; protein kinase C epsilon type; protein kinase C, epsilon; protein kinase C, eta; R75156

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5581

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.92 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q02156

Gene Symbols:
PRKCE

Immunogen:
Recombinant fragment corresponding to a region within amino acids 197 and 606 of PKC epsilon (Uniprot ID#Q02156)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534711

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Antigen:
CaMKI gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Camk1g

Gene Alias:
calcium/calmodulin dependent protein kinase IG; calcium/calmodulin-dependent protein kinase I gamma; calcium/calmodulin-dependent protein kinase IG; calcium/calmodulin-dependent protein kinase type 1G; CaM kinase 1G; CaM kinase I gamma; caM kinase IG; CAMK1G; caMKI gamma; caM-KI gamma; caMKIG; CaMKIgamma; caMKI-gamma; caMK-like CREB kinase III; CLICK III; CLICK3; CLICKIII; CLICK-III; dJ272L16.1; RP1-272L16.2; VWS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
215303, 57172

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q91VB2, Q96NX5

Gene Symbols:
Camk1g

Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 183 and 466 of CaMKI gamma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534713

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Antigen:
HEF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEDD9

Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18003, 4739

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.93 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O35177, Q14511

Gene Symbols:
NEDD9

Immunogen:
Recombinant fragment contains a sequence corresponding to a region within amino acids 115 and 444 of HEF1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG