PIPA535089
beta Arrestin 1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA535089-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA535089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
beta Arrestin 1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARRB1
Gene Alias
1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
408
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P49407
Gene Symbols
ARRB1
Immunogen
KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology
- Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
- Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
- Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
- Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Compare Similar Items
Show Difference
Antigen: beta Arrestin 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARRB1
Gene Alias: 1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 408
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P49407
Gene Symbols: ARRB1
Immunogen: KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
beta Arrestin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARRB1
Gene Alias:
1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
408
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P49407
Gene Symbols:
ARRB1
Immunogen:
KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PCDH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PCDH1
Gene Alias: 2010005A06Rik; AI585920; cadherin-like 1; cadherin-like protein 1; PC42; PCDH1; PCDH42; protocadherin 1; protocadherin 1 (cadherin-like 1); protocadherin 42; protocadherin-1; Protocadherin-42
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5097
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q08174
Gene Symbols: PCDH1
Immunogen: KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PCDH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PCDH1
Gene Alias:
2010005A06Rik; AI585920; cadherin-like 1; cadherin-like protein 1; PC42; PCDH1; PCDH42; protocadherin 1; protocadherin 1 (cadherin-like 1); protocadherin 42; protocadherin-1; Protocadherin-42
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5097
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q08174
Gene Symbols:
PCDH1
Immunogen:
KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Carboxypeptidase B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CPB1
Gene Alias: 0910001A18Rik; 1810063F02Rik; 2210008M23Rik; AI504870; carboxypeptidase B; carboxypeptidase B1; carboxypeptidase B1 (tissue); Cpb; Cpb1; Pancreas-specific protein; pancreatic carboxypeptidase B; pancreatic carboxypeptidase B1; PASP; PCPB; procarboxypeptidase B; protaminase; tissue carboxypeptidase B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1360
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P15086
Gene Symbols: CPB1
Immunogen: KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human CPB1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Carboxypeptidase B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CPB1
Gene Alias:
0910001A18Rik; 1810063F02Rik; 2210008M23Rik; AI504870; carboxypeptidase B; carboxypeptidase B1; carboxypeptidase B1 (tissue); Cpb; Cpb1; Pancreas-specific protein; pancreatic carboxypeptidase B; pancreatic carboxypeptidase B1; PASP; PCPB; procarboxypeptidase B; protaminase; tissue carboxypeptidase B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1360
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P15086
Gene Symbols:
CPB1
Immunogen:
KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human CPB1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FOXA2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FOXA2
Gene Alias: FKHL20; forkhead box A2; forkhead box protein A2; Foxa2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; HNF3B; Hnf-3b; HNF3beta; HNF-3BETA; HNF-3-beta; HNF3-beta; MGC19807; putative; RONU; TCF3B; TCF-3B; transcription factor; transcription factor 3B; transcription factor Foxa2; WHN
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 25099, 3170
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P32182, Q9Y261
Gene Symbols: FOXA2
Immunogen: KLH conjugated synthetic peptide between 380-407 amino acids from the C-terminal region of human FOXA2
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FOXA2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FOXA2
Gene Alias:
FKHL20; forkhead box A2; forkhead box protein A2; Foxa2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3 beta (winged helix transcription factor); hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor-3beta; HNF3B; Hnf-3b; HNF3beta; HNF-3BETA; HNF-3-beta; HNF3-beta; MGC19807; putative; RONU; TCF3B; TCF-3B; transcription factor; transcription factor 3B; transcription factor Foxa2; WHN
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
25099, 3170
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P32182, Q9Y261
Gene Symbols:
FOXA2
Immunogen:
KLH conjugated synthetic peptide between 380-407 amino acids from the C-terminal region of human FOXA2
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG