PIPA538075

Phospho-Synaptotagmin 1 (Ser309) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538075-Each-of-1 In Stock ₹ 42,694.44

PIPA538075 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-Synaptotagmin 1 (Ser309)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SYT1

Gene Alias

SYT, p65, synaptotagmin I

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20979, 6857

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P21579, P46096

Gene Symbols

SYT1

Immunogen

A synthetic phosphopeptide derived from human Synaptotagmin around the phosphorylation site of Ser309 (G-L-SP-D-P)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA538472

--

Img

Thermo Scientific

PIPA538929

--

Img

Thermo Scientific

PIPA538092

--

Img

Thermo Scientific

PIPA538340

--

Img

Thermo Scientific

PIPA538439

--

Img

Thermo Scientific

PIPA538262

--

Img

Thermo Scientific

PIPA538335

--

Img

Thermo Scientific

PIPA538364

--

Description

  • Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538075

--


Antigen:
Phospho-Synaptotagmin 1 (Ser309)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SYT1

Gene Alias:
SYT, p65, synaptotagmin I

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20979, 6857

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P21579, P46096

Gene Symbols:
SYT1

Immunogen:
A synthetic phosphopeptide derived from human Synaptotagmin around the phosphorylation site of Ser309 (G-L-SP-D-P)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538081

--


Antigen:
Phospho-CCR5 (Ser349)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCR5

Gene Alias:
C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CD195 antigen, CHEMR13, CKR5, CMKBR5, HIV-1 fusion co-receptor, MIP-1 alpha receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Immunogen:
A synthetic phosphopeptide derived from human CCR5 around the phosphorylation site of Ser349 (E-I-SP-V-G)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538083

--


Antigen:
Phospho-Crk (Tyr221)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRK

Gene Alias:
Adapter molecule crk, CRKO, Crk-II, P38, Proto-oncogene C-crk

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12928, 1398, 54245

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P46108, Q64010, Q63768

Gene Symbols:
CRK

Immunogen:
A synthetic phosphopeptide derived from human CrkII around the phosphorylation site of Tyr221 (G-P-YP-A-Q)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538086

--


Antigen:
eEF2K

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EEF2K

Gene Alias:
Calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase, EC 2.7.11.20, EF2K, Elongation factor 2 kinase, eEF-2 kinase, eEF-2K, kinase eEF2K

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13631, 25435, 29904

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O00418, O08796, P70531

Gene Symbols:
EEF2K

Immunogen:
A synthetic non-phosphopeptide derived from human eEF2K around the phosphorylation site of Ser366 (T-L-SP-G-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG