PIPA538262

Phospho-BID (Ser78) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538262-Each-of-1 In Stock ₹ 42,694.44

PIPA538262 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-BID (Ser78)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BID

Gene Alias

BH3-interacting domain death agonist, BID, p22 BID

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12122, 637

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P55957, P70444

Gene Symbols

BID

Immunogen

A synthetic phosphopeptide derived from human BID around the phosphorylation site of Ser78 (S-E-SP-Q-E)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
  • Bid is a member of the BCL-2 family of cell death regulators
  • BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
  • BID is also a pro-apoptotic member of the Bcl 2 family
  • BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
  • Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
  • BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538262

--


Antigen:
Phospho-BID (Ser78)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BID

Gene Alias:
BH3-interacting domain death agonist, BID, p22 BID

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12122, 637

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P55957, P70444

Gene Symbols:
BID

Immunogen:
A synthetic phosphopeptide derived from human BID around the phosphorylation site of Ser78 (S-E-SP-Q-E)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538263

--


Antigen:
Phospho-Caldesmon (Ser789)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALD1

Gene Alias:
CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109624, 25687, 800

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q05682, Q62736

Gene Symbols:
CALD1

Immunogen:
A synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789 (V-T-SP-P-T)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538265

--


Antigen:
Phospho-c-Cbl (Tyr774)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBL

Gene Alias:
E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL, CBL, CBL2, RNF55

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12402, 500985, 867

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P22681, P22682

Gene Symbols:
CBL

Immunogen:
A synthetic phosphopeptide derived from human CBL around the phosphorylation site of Tyr774 (D-G-YP-D-V)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538267

--


Antigen:
Phospho-c-Cbl (Tyr674)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBL

Gene Alias:
E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL, CBL, CBL2, RNF55

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12402, 500985, 867

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P22681, P22682

Gene Symbols:
CBL

Immunogen:
A synthetic phosphopeptide derived from human CBL around the phosphorylation site of Tyr674 (A-I-YP-S-L)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG