PIPA538110

Phospho-Cyclin D3 (Thr283) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538110-Each-of-1 In Stock ₹ 42,694.44

PIPA538110 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-Cyclin D3 (Thr283)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CCND3

Gene Alias

CCND3, CGD3, Cyl-3, G1/S-specific cyclin D3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12445, 25193, 896

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P30281, P30282, P48961

Gene Symbols

CCND3

Immunogen

A synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283 (T-S-TP-P-T)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA538361

--

Img

Thermo Scientific

PIPA538452

--

Img

Thermo Scientific

PIPA538472

--

Img

Thermo Scientific

PIPA538439

--

Img

Thermo Scientific

PIPA538929

--

Img

Thermo Scientific

PIPA538358

--

Img

Thermo Scientific

PIPA538340

--

Img

Thermo Scientific

PIPA538075

--

Description

  • Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
  • Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase
  • Hypophosphorylates RB1 in early G(1) phase
  • Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals
  • Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity
  • Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538110

--


Antigen:
Phospho-Cyclin D3 (Thr283)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCND3

Gene Alias:
CCND3, CGD3, Cyl-3, G1/S-specific cyclin D3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12445, 25193, 896

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P30281, P30282, P48961

Gene Symbols:
CCND3

Immunogen:
A synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283 (T-S-TP-P-T)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538113

--


Antigen:
Phospho-FADD (Ser194)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FADD

Gene Alias:
FAS-associating death domain-containing protein, MORT1, Mediator of receptor induced toxicity

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8772

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13158

Gene Symbols:
FADD

Immunogen:
A synthetic phosphopeptide derived from human FADD around the phosphorylation site of Ser194 (A-M-SP-P-M)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538125

--


Antigen:
Phospho-ATF2 (Thr55, Thr73)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF2

Gene Alias:
Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF-2, CREB2, CREBP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11909, 1386, 81647

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15336, P16951, Q00969

Gene Symbols:
ATF2

Immunogen:
A synthetic phosphopeptide derived from human ATF-2 around the phosphorylation site of Thr73 or 55 (D-L-SP-P-L)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538135

--


Antigen:
Phospho-HDAC4 (Ser632)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC4

Gene Alias:
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, histone deacetylase A, DKFZp779K1053, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9, HDAC9B, HDAC9FL, HDRP, histone deacetylase 4/5-related protein, histone deacetylase 7, Histone deacetylase 7B, Histone deacetylase 9, Histone deacetylase-related protein, KIAA0744, MEF-2 interacti, HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR, MEF-2 interacting transcription repressor (MITR) protein, histone deacetylase 4/5-related protein, histone deacetylase 7B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
208727, 363287, 9759

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P56524, Q6NZM9, Q99P99

Gene Symbols:
HDAC4

Immunogen:
A synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser632 (A-Q-SP-S-P)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG