PIPA538282

Phospho-INSR (Tyr1355) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538282-Each-of-1 In Stock ₹ 42,694.44

PIPA538282 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-INSR (Tyr1355)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

INSR

Gene Alias

CD 220, CD220, CD220 antigen, HHF 5, HHF5, human insulin receptor, INSR, INSR, Insulin receptor subunit beta, IR 1, IR, IR-1, IR1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16337, 24954, 3643

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P06213, P15208, P15127

Gene Symbols

INSR

Immunogen

A synthetic phosphopeptide derived from human IR around the phosphorylation site of Tyr1355 (R-S-YP-E-E)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • INSR (insulin receptor, IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment
  • The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis
  • Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin
  • INSR and IGF-1 receptors share major structural and functional similarity
  • The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR
  • In humans, the INSR gene is located on chromosome 19
  • Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.

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Thermo Scientific

PIPA538282

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Antigen:
Phospho-INSR (Tyr1355)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
CD 220, CD220, CD220 antigen, HHF 5, HHF5, human insulin receptor, INSR, INSR, Insulin receptor subunit beta, IR 1, IR, IR-1, IR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16337, 24954, 3643

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P06213, P15208, P15127

Gene Symbols:
INSR

Immunogen:
A synthetic phosphopeptide derived from human IR around the phosphorylation site of Tyr1355 (R-S-YP-E-E)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538284

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Antigen:
Phospho-IRAK1 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRAK1

Gene Alias:
IL-1 Receceptor Associated Kinase, Interleukin-1 receptor-associated kinase 1, mPLK, IRAK, pelle, Pelle homolog, Pelle

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 363520, 3654

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51617, Q62406

Gene Symbols:
IRAK1

Immunogen:
A synthetic phosphopeptide derived from human IRAK1 around the phosphorylation site of Thr387 (R-G-TP-L-A)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538286

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Antigen:
Phospho-IRS1 (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
Insulin receptor substrate 1, IRS-1, IRS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
A synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Ser323 (P-G-SP-F-R)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538289

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Antigen:
JNK1/JNK2/JNK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK9

Gene Alias:
JNK 46, JNK 55, JNK, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2ALPHA, JNK2B, JNK2BETA, JNK3, JNK3A, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 8, MAPK 9, MAPK10, MAPK8, MAPK9, MGC50974, Mitogen activated protein kinase 10, Mitogen activated protein kinase 8, Mitogen activated protein kinase 9, JNK3; JNK3A; PRKM10; p54bSAPK; MAPK10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P45983, P45984, P53779, Q61831, Q91Y86, Q9WTU6, P49185, P49186, P49187

Gene Symbols:
MAPK10, MAPK8, MAPK9

Immunogen:
A synthetic non-phosphopeptide derived from human JNK1/2/3 around the phosphorylation site of Thr183/Tyr185 (M-M-TP-P-YP-V-V)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG