PIPA538311

PAK1/2/3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA538311-Each-of-1 In Stock ₹ 42,694.44

PIPA538311 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

PAK1/2/3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PAK1

Gene Alias

Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, PAK beta,

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18479, 18481, 224105, 29431, 29432, 29433, 5058, 5062, 5063

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75914, Q13153, Q13177, O88643, Q61036, Q8CIN4, P35465, Q62829, Q64303

Gene Symbols

PAK1, PAK2, PAK3

Immunogen

A synthetic peptide derived from the internal region of human PAK1/2/3

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S
  • cerevisiae kinase Ste 20, involved in pheromone signaling
  • The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation
  • There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation
  • Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.

Compare Similar Items

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Img

Thermo Scientific

PIPA538311

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Antigen:
PAK1/2/3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK1

Gene Alias:
Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, PAK beta,

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18479, 18481, 224105, 29431, 29432, 29433, 5058, 5062, 5063

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75914, Q13153, Q13177, O88643, Q61036, Q8CIN4, P35465, Q62829, Q64303

Gene Symbols:
PAK1, PAK2, PAK3

Immunogen:
A synthetic peptide derived from the internal region of human PAK1/2/3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538313

--


Antigen:
Phospho-PDE4D (Ser53, Ser190)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDE4D

Gene Alias:
DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1, cAMP-specific 3′,5′-cyclic phosphodiesterase 4D, cAMP-specific phosphodiesterase PDE4D6, phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238871, 24627, 5144

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q08499, Q01063, P14270

Gene Symbols:
PDE4D

Immunogen:
A synthetic phosphopeptide derived from human PDE4D around the phosphorylation site of Ser190/53 (R-E-SP-F-L)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538316

--


Antigen:
PKA alpha/beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKACB

Gene Alias:
PRKC Pan, Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, PKCB, PRKCB2, Protein kinase C beta type, PKC-B, PKC-beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18747, 18749, 25636, 293508, 5566, 5567

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17612, P22694, P05132, P68181, P27791, P68182

Gene Symbols:
PRKACA, PRKACB

Immunogen:
A synthetic non-phosphopeptide derived from human PKA CAT around the phosphorylation site of threonine197(T-W-TP-L-C)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538317

--


Antigen:
Phospho-Phospholamban (Ser16, Thr17)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
PLN; phospholamban; CMD1P; PLB; cardiac phospholamban; CMH18

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18821, 5350, 64672

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P26678, P61014, P61016

Gene Symbols:
PLN

Immunogen:
A synthetic phosphopeptide derived from human Phospholamban around the phosphorylation site of Ser16 and Thr17 (R-A-SP-TP-I-E)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG