PIPA538693

PAK1/PAK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538693-Each-of-1 In Stock ₹ 42,694.44

PIPA538693 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

PAK1/PAK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PAK2

Gene Alias

Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK1, PAK alpha, Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, PAK beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18479, 224105, 29431, 29432, 5058, 5062

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13153, Q13177, O88643, Q8CIN4, P35465, Q64303

Gene Symbols

PAK1, PAK2

Immunogen

A synthetic non-phosphopeptide derived from human PAK1/2 around the phosphorylation site of Ser199(T-K-SP-V-Y)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S
  • cerevisiae kinase Ste 20, involved in pheromone signaling
  • The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation
  • There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation
  • Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA538693

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Antigen:
PAK1/PAK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK2

Gene Alias:
Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK1, PAK alpha, Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, PAK beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18479, 224105, 29431, 29432, 5058, 5062

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13153, Q13177, O88643, Q8CIN4, P35465, Q64303

Gene Symbols:
PAK1, PAK2

Immunogen:
A synthetic non-phosphopeptide derived from human PAK1/2 around the phosphorylation site of Ser199(T-K-SP-V-Y)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538697

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Antigen:
CERKL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CERKL

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
375298

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q49MI3

Gene Symbols:
CERKL

Immunogen:
A synthetic peptide derived from the internal region of human CERKL

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA538699

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Antigen:
Phospho-RAD51 (Tyr315)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad51

Gene Alias:
AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19361, 5888

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco's PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q06609, Q08297

Gene Symbols:
Rad51

Immunogen:
A synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315 (K-I-YP-D-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA538702

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Antigen:
Phospho-RAD52 (Tyr104)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD52

Gene Alias:
DNA repair protein RAD52 homolog, recombination protein RAD52, rhabdomyosarcoma antigen MU-RMS-40.23

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19365, 5893

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P43351, P43352

Gene Symbols:
RAD52

Immunogen:
A synthetic phosphopeptide derived from human RAD52 around the phosphorylation site of Tyr104 (K-F-YP-V-G)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG