PIPA538362

Phospho-eIF4B (Ser422) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538362-Each-of-1 In Stock ₹ 44,063.40

PIPA538362 - Each of 1

₹ 44,063.40

In Stock

Quantity

1

Base Price: ₹ 44,063.40

GST (18%): ₹ 7,931.412

Total Price: ₹ 51,994.812

Antigen

Phospho-eIF4B (Ser422)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EIF4B

Gene Alias

Aryotic initiation factor 4B, Eukaryotic translation initiation factor 4B, hCG_2014609, eIF4B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1975, 300253, 75705

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P23588, Q8BGD9

Gene Symbols

EIF4B

Immunogen

A synthetic phosphopeptide derived from human eIF4B around the phosphorylation site of Ser422 (T-G-SP-E-S)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • eIF4B is a multidomain eukaryotic translation initiation factor with a range of activities
  • It contains one RRM (RNA recognition) domain, a consensus RNA-binding site (RNP-CS) near the N terminus, and a central domain rich in aspartic acid, arginine, tyrosine, and glycine (DRYG)
  • The DRYG domain of eIF4B helps in self-association and interaction with the p170 subunit of eIF3
  • eIF4B binds to both mRNA and 18S ribosomal RNA and thus acts as a bridge between the mRNA and the 40S ribosomal subunit during translation initiation
  • The ATPase and RNA helicase activity of the DEAD box protein eIF4A is stimulated by eIF4B and thus functions in close association with eIF4F, a heterotrimeric protein that binds to mRNA cap structure and unwinds inhibitory secondary structure in the 5′ untranslated region of eucaryotic mRNAs in an ATP-dependent manner
  • Ubiquitous expression is seen in most tissues.

Compare Similar Items

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Img

Thermo Scientific

PIPA538362

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Antigen:
Phospho-eIF4B (Ser422)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4B

Gene Alias:
Aryotic initiation factor 4B, Eukaryotic translation initiation factor 4B, hCG_2014609, eIF4B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1975, 300253, 75705

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P23588, Q8BGD9

Gene Symbols:
EIF4B

Immunogen:
A synthetic phosphopeptide derived from human eIF4B around the phosphorylation site of Ser422 (T-G-SP-E-S)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538364

--


Antigen:
Phospho-IRS1 (Ser794)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
Insulin receptor substrate 1, IRS-1, IRS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
A synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Ser794 (S-T-SP-S-G)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538365

--


Antigen:
Phospho-LAT (Tyr171)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAT

Gene Alias:
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16797, 27040

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43561, O54957

Gene Symbols:
LAT

Immunogen:
A synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr171 (D-D-YP-V-N)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538367

--


Antigen:
Phospho-LKB1 (Thr189)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19, STK11, LKB1, PJS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 6794

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
A synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of throsine 189 (G-G-TP-L-K)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG