PIPA538096
Phospho-4EBP1 (Ser64) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA538096-Each-of-1 | In Stock | ₹ 42,694.44 |
PIPA538096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,694.44
GST (18%): ₹ 7,684.999
Total Price: ₹ 50,379.439
Antigen
Phospho-4EBP1 (Ser64)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EIF4EBP1
Gene Alias
4EBP1, EIF4EBP1, Eukaryotic translation initiation factor 4E binding protein 1, Insulin-stimulated EIF-4E binding protein PHAS-I, P/OKCL.6, PHAS-1, PHAS-I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116636, 13685, 1978
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q13541, Q60876, Q62622
Gene Symbols
EIF4EBP1
Immunogen
A synthetic phosphopeptide derived from human 4E-BP1 around the phosphorylation site of Ser64 (R-N-SP-P-V)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Eukaryotic initiation factor 4E binding protein 1 (4E-BP1), also known as PHAS, is a ∽20 kDa member of a family of eIF4E-binding proteins whose binding affinity to eIF4E is regulated by its phosphorylation
- It inhibits cap-dependent translation by binding to eIF4E on the same site that overlaps the binding site for eIF4G, preventing its binding to the latter and eventually leading to an increase in mRNA translation
- The phosphorylation of 4E-BP1 is critical in determining cell fate by controlling translation initiation and apoptotic potency
- 4E-BP1 is hyperphosphorylated in response to several external stimuli including hormones, growth factors, mitogens, cytokines and G-protein-coupled receptors and in response to stress conditions including nutrient deprivation
- The phosphorylation of these sites is believed to occur in an orderly fashion where phosphorylation of threonine 37 and 46 by FRAP/mTOR is a priming step for subsequent phosphorylation of 4E-BP1 at the carboxy-terminal sites
- Under normoxic conditions, increased VEGF expression, resulting from inhibition of 4E-BP1, contributes to efficient angiogenesis and metastatic brain growth through activated integrin alphav beta3.
Compare Similar Items
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Antigen: Phospho-4EBP1 (Ser64)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF4EBP1
Gene Alias: 4EBP1, EIF4EBP1, Eukaryotic translation initiation factor 4E binding protein 1, Insulin-stimulated EIF-4E binding protein PHAS-I, P/OKCL.6, PHAS-1, PHAS-I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116636, 13685, 1978
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13541, Q60876, Q62622
Gene Symbols: EIF4EBP1
Immunogen: A synthetic phosphopeptide derived from human 4E-BP1 around the phosphorylation site of Ser64 (R-N-SP-P-V)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-4EBP1 (Ser64)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF4EBP1
Gene Alias:
4EBP1, EIF4EBP1, Eukaryotic translation initiation factor 4E binding protein 1, Insulin-stimulated EIF-4E binding protein PHAS-I, P/OKCL.6, PHAS-1, PHAS-I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116636, 13685, 1978
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13541, Q60876, Q62622
Gene Symbols:
EIF4EBP1
Immunogen:
A synthetic phosphopeptide derived from human 4E-BP1 around the phosphorylation site of Ser64 (R-N-SP-P-V)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Mammaglobin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SCGB2A1
Gene Alias: LACRYGLOBIN, MGB2, MAMMAGLOBIN 2, MAMMAGLOBIN B, secretoglobin family 2A member 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4246
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O75556
Gene Symbols: SCGB2A1
Immunogen: A synthetic peptide derived from human Mammaglobin B
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Mammaglobin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SCGB2A1
Gene Alias:
LACRYGLOBIN, MGB2, MAMMAGLOBIN 2, MAMMAGLOBIN B, secretoglobin family 2A member 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4246
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O75556
Gene Symbols:
SCGB2A1
Immunogen:
A synthetic peptide derived from human Mammaglobin B
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Acetyl-CoA Carboxylase (Ser80)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACACA
Gene Alias: ACAC, ACACA, ACC-alpha, ACCA, Acetyl-CoA carboxylase 1, EC 6.3.4.14, EC 6.4.1.2, ACC1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107476, 31, 60581
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13085, Q5SWU9, P11497
Gene Symbols: ACACA
Immunogen: A synthetic phosphopeptide derived from human ACC1 around the phosphorylation site of Ser79 (S-M-SP-G-L)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Acetyl-CoA Carboxylase (Ser80)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACACA
Gene Alias:
ACAC, ACACA, ACC-alpha, ACCA, Acetyl-CoA carboxylase 1, EC 6.3.4.14, EC 6.4.1.2, ACC1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107476, 31, 60581
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13085, Q5SWU9, P11497
Gene Symbols:
ACACA
Immunogen:
A synthetic phosphopeptide derived from human ACC1 around the phosphorylation site of Ser79 (S-M-SP-G-L)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cyclin D3 (Thr283)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCND3
Gene Alias: CCND3, CGD3, Cyl-3, G1/S-specific cyclin D3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12445, 25193, 896
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P30281, P30282, P48961
Gene Symbols: CCND3
Immunogen: A synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283 (T-S-TP-P-T)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cyclin D3 (Thr283)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCND3
Gene Alias:
CCND3, CGD3, Cyl-3, G1/S-specific cyclin D3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12445, 25193, 896
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P30281, P30282, P48961
Gene Symbols:
CCND3
Immunogen:
A synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283 (T-S-TP-P-T)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG