PIPA538527

Phospho-STAT5 alpha (Ser725) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538527-Each-of-1 In Stock ₹ 42,694.44

PIPA538527 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-STAT5 alpha (Ser725)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT5A

Gene Alias

Signal transducer and activator of transcription 5A, STAT5A, STAT5, Signal transducer and activator of transcription 5B, STAT5B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24918, 6776

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P42229, Q62771

Gene Symbols

STAT5A

Immunogen

A synthetic phosphopeptide derived from human STAT5A around the phosphorylation site of Ser725 (A-P-SP-P-V)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA538527

--


Antigen:
Phospho-STAT5 alpha (Ser725)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
Signal transducer and activator of transcription 5A, STAT5A, STAT5, Signal transducer and activator of transcription 5B, STAT5B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24918, 6776

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P42229, Q62771

Gene Symbols:
STAT5A

Immunogen:
A synthetic phosphopeptide derived from human STAT5A around the phosphorylation site of Ser725 (A-P-SP-P-V)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA538529

--


Antigen:
AKAP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKAP10

Gene Alias:
A-kinase anchor protein 10, mitochondrial, AKAP-10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, Protein kinase A-anchoring protein 10, PRKA10, AKAP10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11216, 360540, 56697

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43572, O88845

Gene Symbols:
AKAP10

Immunogen:
A synthetic peptide derived from the internal region of human AKAP10

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538531

--


Antigen:
Phospho-Tryptophan Hydroxylase (Ser58)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPH1

Gene Alias:
TPRH, TRPH, L-tryptophan hydroxylase, indoleacetic acid-5-hydroxylase, tryptophan 5-hydroxylase 1, tryptophan 5-monooxygenase 1, tryptophan hydroxylase (tryptophan 5-monooxygenase)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21990, 24848, 7166

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17752, P17532, P09810

Gene Symbols:
TPH1

Immunogen:
A synthetic phosphopeptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser58 (R-N-SP-E-F)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA538534

--


Antigen:
Phospho-Tryptophan Hydroxylase (Ser260)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPH1

Gene Alias:
TPRH, TRPH, L-tryptophan hydroxylase, indoleacetic acid-5-hydroxylase, tryptophan 5-hydroxylase 1, tryptophan 5-monooxygenase 1, tryptophan hydroxylase (tryptophan 5-monooxygenase)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21990, 24848, 7166

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17752, P17532, P09810

Gene Symbols:
TPH1

Immunogen:
A synthetic phosphopeptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser260 (H-S-SP-D-P)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG