PIPA552776

ARHGEF11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA552776-Each-of-1 In Stock ₹ 47,015.22

PIPA552776 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

ARHGEF11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARHGEF11

Gene Alias

Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9826

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O15085

Gene Symbols

ARHGEF11

Immunogen

Recombinant protein corresponding to Human ARHGEF11

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LQAEIDSRLR NSEDARGVLC EAQEAAMPEI QEQIHDYRTK RTLGLGSLYG ENDLLDLDGD PLRERQVAEK QLAALGDILS KYEEDRSAPM DFALNTYMSH AGIRLREARP SNTAEKAQSA PDKDKWLPFF PKTKKSSNSK KEQDA Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 88%
  • ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
  • It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
  • It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
  • ARHGEF11 increases glutamate transport 4-fold
  • It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
  • It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
  • It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA552776

--


Antigen:
ARHGEF11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9826

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15085

Gene Symbols:
ARHGEF11

Immunogen:
Recombinant protein corresponding to Human ARHGEF11

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552777

--


Antigen:
LETM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LETM1

Gene Alias:
LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial; leucine zipper and EF-hand containing transmembrane protein 1; leucine zipper-EF-hand containing transmembrane protein 1; leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; Mitochondrial proton/calcium exchanger protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3954

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O95202

Gene Symbols:
LETM1

Immunogen:
Recombinant protein corresponding to Human LETM1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552778

--


Antigen:
ARMC10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Armc10

Gene Alias:
2810037c14rik; armadillo repeat containing 10; armadillo repeat-containing protein 10; ARMC10; PNAS112; PNAS-112; PSEC0198; RGD1305915; specific splicing variant involved in hepatocarcinogenesis; splicing variant involved in hepatocarcinogenesis protein; Svh; SVH protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296758, 67211, 83787

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
B1WBW4, Q8N2F6, Q9D0L7

Gene Symbols:
Armc10

Immunogen:
Recombinant protein corresponding to Human ARMC10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA552780

--


Antigen:
TMEM24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C2CD2L

Gene Alias:
1300006O23Rik; C2 calcium-dependent domain containing 2-like; C2 domain-containing protein 2-like; C2 domain-containing protein 2-like; phospholipid transfer protein C2CD2L; c2cd2 like; C2cd2l; C2CD2-like; DLNB23; KIAA0285; Phospholipid transfer protein C2CD2L; tmem24; Transmembrane protein 24; zgc:153961

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9854

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O14523

Gene Symbols:
C2CD2L

Immunogen:
Recombinant protein corresponding to Human TMEM24

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG