PIPA553222

Kir3.4 (KCNJ5) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA553222-Each-of-1 In Stock ₹ 47,015.22

PIPA553222 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Kir3.4 (KCNJ5)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNJ5

Gene Alias

cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3762

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P48544

Gene Symbols

KCNJ5

Immunogen

Recombinant protein corresponding to Human KCNJ5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: TPVLTLEKGF YEVDYNTFHD TYETNTPSCC AKELAEMKRE GRLLQYLPSP PLLGGCAEAG LDAEAEQNEE DEPKGLGG Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 85%
  • G protein-coupled inwardly rectifying potassium channels (Kir3.1 through Kir3.4) are coupled to numerous neurotransmitter receptors in the brain and are abundantly expressed in the olfactory bulb, hippocampus, neocortex, dentate gyrus, cerebellar cortex and thalamus regions of the brain
  • Also known as GIRK, Kir3 potassium channels localize to the soma and dendrites as well as axons of neurons
  • Liberated Gbg subunits from G protein heterotrimers bind to and regulate Kir3 channel activity
  • Gb3- and Gb4-containing Gbg dimers bind directly to cytoplasmic domains of Kir3 proteins and increase the K+ current while Gb5-containing Gbg dimers inhibit Kir3 K+ current
  • Kir3 activity is also inhibited by tyrosine phosphorylation
  • Brain-derived neurotrophic factor activates receptor tyrosine kinase B, which then phosphorylates Kir3 tyrosine residues, effectively inactivating the Kir3 channels.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA553222

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Antigen:
Kir3.4 (KCNJ5)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNJ5

Gene Alias:
cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3762

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P48544

Gene Symbols:
KCNJ5

Immunogen:
Recombinant protein corresponding to Human KCNJ5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553223

--


Antigen:
MCEMP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MCEMP1

Gene Alias:
C19orf59; mast cell expressed membrane protein 1; mast cell-expressed membrane protein 1; MCEMP1; MGC132456

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
199675

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8IX19

Gene Symbols:
MCEMP1

Immunogen:
Recombinant protein corresponding to Human MCEMP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA553224

--


Antigen:
SLC13A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC13A3

Gene Alias:
hNaDC3; hypothetical protein zgc:77173; mNaDC3; Na(+)/dicarboxylate cotransporter 3; Nadc3; NaDC-3; rNaDC3; SDCT2; slc13a3; sodium-dependent high affinity dicarboxylate transporter 3; sodium-dependent high-affinity dicarboxylate transporter 2; sodium-dependent high-affinity dicarboxylate transporter 3; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; solute carrier family 13 member 3; zgc:77173

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64849

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8WWT9

Gene Symbols:
SLC13A3

Immunogen:
Recombinant protein corresponding to Human SLC13A3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553227

--


Antigen:
ARL6IP6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARL6IP6

Gene Alias:
2310057C01Rik; 2610529A11Rik; ADP ribosylation factor like GTPase 6 interacting protein 6; ADP-ribosylation factor GTPase 6 interacting protein 6; ADP-ribosylation factor like GTPase 6 interacting protein 6; ADP-ribosylation factor-like 6 interacting protein 6; ADP-ribosylation factor-like protein 6-interacting protein 6; ADP-ribosylation-like factor 6 interacting protein 6; ADP-ribosylation-like factor 6-interacting protein 6; AIP6; aip-6; ARL-6-interacting protein 6; Arl6ip6; PFAAP1; Phosphonoformate immuno-associated protein 1; regulated by phosphonoformate

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
151188

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8N6S5

Gene Symbols:
ARL6IP6

Immunogen:
Recombinant protein corresponding to Human ARL6IP6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG