PIPA553594

Kir3.4 (KCNJ5) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553594-Each-of-1 In Stock ₹ 50,052.60

PIPA553594 - Each of 1

₹ 50,052.60

In Stock

Quantity

1

Base Price: ₹ 50,052.60

GST (18%): ₹ 9,009.468

Total Price: ₹ 59,062.068

Antigen

Kir3.4 (KCNJ5)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNJ5

Gene Alias

cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3762

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P48544

Gene Symbols

KCNJ5

Immunogen

Recombinant protein corresponding to Human KCNJ5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VTPWDPKKIP KQARDYVPIA TDRTRLLAEG KKPRQRYMEK SGKCNVHHGN VQETY Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%
  • G protein-coupled inwardly rectifying potassium channels (Kir3.1 through Kir3.4) are coupled to numerous neurotransmitter receptors in the brain and are abundantly expressed in the olfactory bulb, hippocampus, neocortex, dentate gyrus, cerebellar cortex and thalamus regions of the brain
  • Also known as GIRK, Kir3 potassium channels localize to the soma and dendrites as well as axons of neurons
  • Liberated Gbg subunits from G protein heterotrimers bind to and regulate Kir3 channel activity
  • Gb3- and Gb4-containing Gbg dimers bind directly to cytoplasmic domains of Kir3 proteins and increase the K+ current while Gb5-containing Gbg dimers inhibit Kir3 K+ current
  • Kir3 activity is also inhibited by tyrosine phosphorylation
  • Brain-derived neurotrophic factor activates receptor tyrosine kinase B, which then phosphorylates Kir3 tyrosine residues, effectively inactivating the Kir3 channels.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA553594

--


Antigen:
Kir3.4 (KCNJ5)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNJ5

Gene Alias:
cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3762

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P48544

Gene Symbols:
KCNJ5

Immunogen:
Recombinant protein corresponding to Human KCNJ5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553595

--


Antigen:
EPSTI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPSTI1

Gene Alias:
2310046K10Rik; 5033415K03Rik; BRESI1; epithelial stromal interaction 1; epithelial stromal interaction 1 (breast); epithelial-stromal interaction protein 1; EPSTI1; RGD1563207; Unknown (protein for IMAGE:7987136)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
94240

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96J88

Gene Symbols:
EPSTI1

Immunogen:
Recombinant protein corresponding to Human EPSTI1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553596

--


Antigen:
IRS4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS4

Gene Alias:
160 kDa phosphotyrosine protein; Insulin receptor substrate 4; Irs4; IRS-4; Phosphoprotein of 160 kDa; pp160; py160; RP23-415G1.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8471

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O14654

Gene Symbols:
IRS4

Immunogen:
Recombinant protein corresponding to Human IRS4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA553598

--


Antigen:
CDO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDON

Gene Alias:
CAM-related/down-regulated by oncogenes; Cd0; Cdo; CDON; Cdon homolog; CDON1; cell adhesion associated, oncogene regulated; cell adhesion molecule-related/down-regulated by oncogenes; HPE11; immunoglobulin superfamily member; immunoglobulin superfamily member CDO; oncogene-regulated cell adhesion molecule; ORCAM; surface glycoprotein, Ig superfamily member

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50937

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q4KMG0

Gene Symbols:
CDON

Immunogen:
Recombinant protein corresponding to Human CDO

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG