PIPA553315
SRPK2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA553315-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA553315 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
SRPK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SRPK2
Gene Alias
AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6733
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.10 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P78362
Gene Symbols
SRPK2
Immunogen
Recombinant protein corresponding to Human SRPK2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QQLDDEDDDE EDCPNPEEYN LDEPNAESDY TYSSSYEQFN GELPNGRHKI PESQFPEFST SLFSGSLEPV ACGSVLSEGS PLTEQEESSP SHDRSRTVSA SSTGDLPKAK TRAADLLVNP L Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%
- SRPK2, along with SRPK1, is most likely the cellular protein kinase mediating HBV core protein phosphorylation during viral infection
- It therefore represents an important host cell target for therapeutic intervention in HBV infection
- Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression
- This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression
- Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation
- Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28
- Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles .
Compare Similar Items
Show Difference
Antigen: SRPK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRPK2
Gene Alias: AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6733
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.10 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P78362
Gene Symbols: SRPK2
Immunogen: Recombinant protein corresponding to Human SRPK2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SRPK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRPK2
Gene Alias:
AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6733
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.10 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P78362
Gene Symbols:
SRPK2
Immunogen:
Recombinant protein corresponding to Human SRPK2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TYW1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TYW1
Gene Alias: Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; radical S-adenosyl methionine and flavodoxin domains 1; RGD1310420; RSAFD1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog (S. cerevisiae); tRNA-yW synthesizing protein 1 homolog A; tRNA-yW-synthesizing protein; TYW1; TYW1A; YPL207W
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55253
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NV66
Gene Symbols: TYW1
Immunogen: Recombinant protein corresponding to Human TYW1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TYW1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TYW1
Gene Alias:
Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; radical S-adenosyl methionine and flavodoxin domains 1; RGD1310420; RSAFD1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog (S. cerevisiae); tRNA-yW synthesizing protein 1 homolog A; tRNA-yW-synthesizing protein; TYW1; TYW1A; YPL207W
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55253
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9NV66
Gene Symbols:
TYW1
Immunogen:
Recombinant protein corresponding to Human TYW1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LRIG2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lrig2
Gene Alias: 4632419I10Rik; BB096938; Kiaa0806; leucine rich repeats and immunoglobulin like domains 2; leucine-rich repeats and immunoglobulin like domains 2; leucine-rich repeats and immunoglobulin-like domains 2; leucine-rich repeats and immunoglobulin-like domains protein 2; LIG2; LIG-2; Lrig2; UFS2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9860
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O94898
Gene Symbols: Lrig2
Immunogen: Recombinant protein corresponding to Human LRIG2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LRIG2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lrig2
Gene Alias:
4632419I10Rik; BB096938; Kiaa0806; leucine rich repeats and immunoglobulin like domains 2; leucine-rich repeats and immunoglobulin like domains 2; leucine-rich repeats and immunoglobulin-like domains 2; leucine-rich repeats and immunoglobulin-like domains protein 2; LIG2; LIG-2; Lrig2; UFS2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9860
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O94898
Gene Symbols:
Lrig2
Immunogen:
Recombinant protein corresponding to Human LRIG2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: WNK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WNK2
Gene Alias: 1810073P09Rik; Antigen NY-CO-43; AW122246; ESTM15; Kiaa1760; kinase deficient protein; LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK2; mitogen-activated protein kinase kinase kinase; mKIAA1760; NY-CO-43; P/OKcl.13; PRKWNK2; protein kinase lysine-deficient 2; Protein kinase with no lysine 2; protein kinase, lysine deficient 2; RGD1307284; SDCCAG43; Serine/threonine-protein kinase WNK2; serologically defined colon cancer antigen 43; WNK lysine deficient protein kinase 2; Wnk2; X83337
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 65268
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9Y3S1
Gene Symbols: WNK2
Immunogen: Recombinant protein corresponding to Human WNK2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
WNK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WNK2
Gene Alias:
1810073P09Rik; Antigen NY-CO-43; AW122246; ESTM15; Kiaa1760; kinase deficient protein; LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK2; mitogen-activated protein kinase kinase kinase; mKIAA1760; NY-CO-43; P/OKcl.13; PRKWNK2; protein kinase lysine-deficient 2; Protein kinase with no lysine 2; protein kinase, lysine deficient 2; RGD1307284; SDCCAG43; Serine/threonine-protein kinase WNK2; serologically defined colon cancer antigen 43; WNK lysine deficient protein kinase 2; Wnk2; X83337
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
65268
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9Y3S1
Gene Symbols:
WNK2
Immunogen:
Recombinant protein corresponding to Human WNK2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG