PIPA555771

CDCA8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA555771-Each-of-1 In Stock ₹ 50,737.08

PIPA555771 - Each of 1

₹ 50,737.08

In Stock

Quantity

1

Base Price: ₹ 50,737.08

GST (18%): ₹ 9,132.674

Total Price: ₹ 59,869.754

Antigen

CDCA8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDCA8

Gene Alias

4831429J16Rik; AU044747; BOR; Borealin; Cdca8; cell division cycle associated 8; cell division cycle-associated protein 8; D4Ertd421e; Dasra B; DasraB; dasra-B; embryonic stem cell-related; hDasra-B; MESrg; MESRGP; PESCRG3; Pluripotent embryonic stem cell-related gene 3 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55143

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q53HL2

Gene Symbols

CDCA8

Immunogen

Recombinant protein corresponding to Human CDCA8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PLKSAKTRKV IQVDEMIVEE EEEEENERKN LQTARVKRCP PSKKRTQSIQ GKGKGKRSSR ANTVTPAVGR LEVSMVKPTP GLTPRFDSR Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 66%
  • CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle
  • The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division
  • It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase
  • CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues
  • In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation
  • Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53
  • Its aberrant expression is linked to a poor prognosis for gastric cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA555771

--


Antigen:
CDCA8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDCA8

Gene Alias:
4831429J16Rik; AU044747; BOR; Borealin; Cdca8; cell division cycle associated 8; cell division cycle-associated protein 8; D4Ertd421e; Dasra B; DasraB; dasra-B; embryonic stem cell-related; hDasra-B; MESrg; MESRGP; PESCRG3; Pluripotent embryonic stem cell-related gene 3 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55143

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q53HL2

Gene Symbols:
CDCA8

Immunogen:
Recombinant protein corresponding to Human CDCA8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA555772

--


Antigen:
PARP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PARP10

Gene Alias:
ADP-ribosyltransferase diphtheria toxin-like 10; ARTD10; FLJ14464; LOC102548778; Parp10; PARP-10; poly (ADP-ribose) polymerase family, member 10; poly [ADP-ribose] polymerase 10; poly [ADP-ribose] polymerase 10-like; poly(ADP-ribose) polymerase family member 10; Protein mono-ADP-ribosyltransferase PARP10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84875

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q53GL7

Gene Symbols:
PARP10

Immunogen:
Recombinant protein corresponding to Human PARP10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA555773

--


Antigen:
WRAP53

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WRAP53

Gene Alias:
BC021790; DKCB3; TCAB1; Telomerase Cajal body protein 1; WD repeat containing antisense to TP53; WD repeat containing, antisense to TP53; WD repeat containing, antisense to Trp53; WD repeat domain 79; WD repeat-containing protein 79; WD repeat-containing protein WRAP53; WD40 protein Wrap53; WD40 repeat-containing protein antisense to TP53; WD40 repeat-containing protein antisense to TP53 gene; WD40 repeat-containing protein antisense to TP53 gene homolog; WD40 repeat-containing protein encoded by RNA antisense to p53; WD40 repeat-containing protein encoding RNA antisense to p53; Wdr79; WRAP53; WRAP53beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55135

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
Lot-Specific

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BUR4

Gene Symbols:
WRAP53

Immunogen:
Recombinant protein corresponding to Human WRAP53

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA555774

--


Antigen:
MYOM3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Myom3

Gene Alias:
8430427K15Rik; Gm434; MYOM3; myomesin 3; Myomesin family member 3; myomesin family, member 3; myomesin-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
127294

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5VTT5

Gene Symbols:
Myom3

Immunogen:
Recombinant protein corresponding to Human MYOM3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG