PIPA555808

CDCA8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA555808-Each-of-1 In Stock ₹ 50,309.28

PIPA555808 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

CDCA8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDCA8

Gene Alias

4831429J16Rik; AU044747; BOR; Borealin; Cdca8; cell division cycle associated 8; cell division cycle-associated protein 8; D4Ertd421e; Dasra B; DasraB; dasra-B; embryonic stem cell-related; hDasra-B; MESrg; MESRGP; PESCRG3; Pluripotent embryonic stem cell-related gene 3 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55143

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q53HL2

Gene Symbols

CDCA8

Immunogen

Recombinant protein corresponding to Human CDCA8

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AKTNSLRRRK LASFLKDFDR EVEIRIKQIE SDRQNLLKEV DNLYNIEILR LPKALREMNW LDYFALGGNK QALEEAATAD LDITEINKLT AE Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%
  • CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle
  • The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division
  • It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase
  • CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues
  • In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation
  • Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53
  • Its aberrant expression is linked to a poor prognosis for gastric cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA555808

--


Antigen:
CDCA8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDCA8

Gene Alias:
4831429J16Rik; AU044747; BOR; Borealin; Cdca8; cell division cycle associated 8; cell division cycle-associated protein 8; D4Ertd421e; Dasra B; DasraB; dasra-B; embryonic stem cell-related; hDasra-B; MESrg; MESRGP; PESCRG3; Pluripotent embryonic stem cell-related gene 3 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55143

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q53HL2

Gene Symbols:
CDCA8

Immunogen:
Recombinant protein corresponding to Human CDCA8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555809

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Antigen:
OPLAH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OPLAH

Gene Alias:
1700010G02Rik; 5-OPase; 5-oxo-L-prolinase; 5-oxoprolinase; 5-oxoprolinase (ATP-hydrolysing); OPLA; Oplah; OPLAHD; pyroglutamase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26873

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O14841

Gene Symbols:
OPLAH

Immunogen:
Recombinant protein corresponding to Human OPLAH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA555811

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Antigen:
PLEKHG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLEKHG1

Gene Alias:
ARHGEF41; KIAA1209; pleckstrin homology and RhoGEF domain containing G1; pleckstrin homology domain containing, family G (with RhoGef domain) member 1; pleckstrin homology domain-containing family G member 1; PLEKHG1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57480

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9ULL1

Gene Symbols:
PLEKHG1

Immunogen:
Recombinant protein corresponding to Human PLEKHG1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Antigen:
FMNL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FMNL1

Gene Alias:
8030453N10Rik; AI553564; C17orf1; C17orf1B; CLL-associated antigen KW-13; FHOD4; Fmnl; Fmnl1; Fnrl; formin like 1; formin-like 1; formin-like protein 1; formin-related gene in leukocytes; formin-related protein; Frl; FRL1; Frls; KW-13; Leukocyte formin; lymphocyte specific formin related protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
752

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O95466

Gene Symbols:
FMNL1

Immunogen:
Recombinant protein corresponding to Human FMNL1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG