PIPA564714

Phospho-SPHK1 (Ser225) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA564714-Each-of-1 In Stock ₹ 44,277.30

PIPA564714 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

Phospho-SPHK1 (Ser225)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9NYA1

Gene Symbols

SPHK1

Immunogen

A synthesized peptide derived from human SPHK1 (Phospho-Ser225)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Phospho-SPHK1 (Ser225) Polyclonal Antibody detects endogenous levels of SPHK1 only when phosphorylated at Ser225
  • SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
  • Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
  • S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Compare Similar Items

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Thermo Scientific

PIPA564714

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Antigen:
Phospho-SPHK1 (Ser225)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8877

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
A synthesized peptide derived from human SPHK1 (Phospho-Ser225)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA564715

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Antigen:
Phospho-SRC1 (Thr1179)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCOA1

Gene Alias:
ASV; bHLHe42; bHLHe74; class E basic helix-loop-helix protein 74; c-SRC; F-SRC-1; Hin-2 protein; KAT13A; mNRC-1; NCOA1; NCoA-1; Nuclear receptor coactivator 1; nuclear receptor coactivator protein 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; Src1; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17977, 8648

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P70365, Q15788

Gene Symbols:
NCOA1

Immunogen:
A synthesized peptide derived from human SRC-1 (Phospho-Thr1179)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA564716

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Antigen:
Phospho-SREBP2 (Ser455)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SREBF2

Gene Alias:
AI608257; bHLHd2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20788, 300095, 6721

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q12772, Q3T1I5, Q3U1N2

Gene Symbols:
SREBF2

Immunogen:
A synthesized peptide derived from human SREBP-2 (Phospho-Ser455)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564717

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Antigen:
Phospho-SRF (Thr159)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRF

Gene Alias:
AW049942; AW240594; c-fos serum response element-binding transcription factor; MCM1; minichromosome maintenance 1 homolog; OTTHUMP00000039820; RGD1559787; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); Srf

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20807, 6722

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P11831, Q9JM73

Gene Symbols:
SRF

Immunogen:
A synthesized peptide derived from human SRF (Phospho-Thr159)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG