PIPA564770

Phospho-SHC (Tyr349, Tyr350) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA564770-Each-of-1 In Stock ₹ 44,705.10

PIPA564770 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-SHC (Tyr349, Tyr350)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHC1

Gene Alias

FLJ26504; OTTHUMP00000035472; p66; P66shc; RP11-307C12.1; SH2 domain protein C1; SHC; SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1; SHC adaptor protein 1; SHC1; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; src homology 2 domain-containing transforming protein C1; src homology 2 domain-containing-transforming protein C1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20416, 6464, 85385

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P29353, P98083, Q5M824

Gene Symbols

SHC1

Immunogen

A synthesized peptide derived from human SHC1 (Phospho-Tyr349+Tyr350)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA562088

--

Img

Thermo Scientific

PIPA564732

--

Img

Thermo Scientific

PIPA561797

--

Img

Thermo Scientific

PIPA562326

--

Img

Thermo Scientific

PIPA562211

--

Img

Thermo Scientific

PIPA564810

--

Img

Thermo Scientific

PIPA564674

--

Img

Thermo Scientific

PIPA564737

--

Description

  • Phospho-SHC (Tyr349, Tyr350) Polyclonal Antibody detects endogenous levels of SHC only when phosphorylated at Tyr349, Tyr350
  • Skp2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex
  • Skp2 is essential for the G1-S transition in both transformed cells and diploid fibroblasts
  • Biochemical and genetic experiments have demonstrated that Skp2 is required for the ubiquitination and consequent degradation of p27 in cultured mammalian cells and in vitro reconstitution assays
  • In normal tissues, Skp2 is expressed in tonsil and placenta
  • In tumor tissues, Skp2 is expressed widely, in some colon, prostate, pancreas, and skin cancers, with high expression in lung, breast, ovarian, and endometrial cancers
  • Research suggests that Skp2 plays a role in oncogenesis, particularly in the pathogenesis of lymphomas and breast cancers.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA564770

--


Antigen:
Phospho-SHC (Tyr349, Tyr350)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHC1

Gene Alias:
FLJ26504; OTTHUMP00000035472; p66; P66shc; RP11-307C12.1; SH2 domain protein C1; SHC; SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1; SHC adaptor protein 1; SHC1; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; src homology 2 domain-containing transforming protein C1; src homology 2 domain-containing-transforming protein C1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20416, 6464, 85385

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29353, P98083, Q5M824

Gene Symbols:
SHC1

Immunogen:
A synthesized peptide derived from human SHC1 (Phospho-Tyr349+Tyr350)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564771

--


Antigen:
Phospho-VASP (Thr278)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VASP

Gene Alias:
Enah/Vasp-like; I79_012660; Unknown (protein for MGC:127789); vasodilator stimulated phosphoprotein; vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein (VASP); VASP

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22323, 361517, 7408

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P50552, P70460

Gene Symbols:
VASP

Immunogen:
A synthesized peptide derived from human VASP (Phospho-Thr278)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564773

--


Antigen:
Phospho-ATM (Ser1987)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11920

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q62388

Gene Symbols:
ATM

Immunogen:
A synthesized peptide derived from human ATM (Phospho-Ser1987)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA564777

--


Antigen:
Phospho-Connexin 43 (Ser279)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJA1

Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2697

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17302

Gene Symbols:
GJA1

Immunogen:
A synthesized peptide derived from human Connexin 43 (Phospho-Ser279)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG