PIPA567178

APOBEC3C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA567178-Each-of-1 In Stock ₹ 47,015.22

PIPA567178 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

APOBEC3C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOBEC3C

Gene Alias

A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27350

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NRW3

Gene Symbols

APOBEC3C

Immunogen

Recombinant Human APOBEC3C

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: NLWEANDRNET WLCFTVEGIK RRSVVS Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 41%
  • APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
  • The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
  • Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
  • Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
  • Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
  • Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
  • This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA567178

--


Antigen:
APOBEC3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOBEC3C

Gene Alias:
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27350

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NRW3

Gene Symbols:
APOBEC3C

Immunogen:
Recombinant Human APOBEC3C

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567180

--


Antigen:
ZNF398

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF398

Gene Alias:
KIAA1339; P51; P71; ZER6; zinc finger DNA binding protein p52/p71; zinc finger DNA binding protein ZER6; zinc finger DNA-binding protein p52/p71; Zinc finger protein 398; zinc finger-estrogen receptor interaction, clone 6; ZNF398

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57541

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8TD17

Gene Symbols:
ZNF398

Immunogen:
Recombinant Human ZNF398

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA567181

--


Antigen:
ITGB1BP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB1BP1

Gene Alias:
AI449260; AU019480; bodenin; DKFZp686K08158; Icap1; ICAP-1; ICAP1A; ICAP-1A; ICAP-1alpha; ICAP1B; ICAP-1B; integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; integrin cytoplasmic domain-associated protein 1-alpha; integrin cytoplasmic domain-associated protein 1-beta; integrin subunit beta 1 binding protein 1; ITGB1BP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9270

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O14713

Gene Symbols:
ITGB1BP1

Immunogen:
Recombinant Human ITGB1BP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA567183

--


Antigen:
FAM59B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAREM2

Gene Alias:
FAM59B; family with sequence similarity 59, member B; Garem2; Gareml; Gm444; GRB2 associated regulator of MAPK1 2; GRB2 associated regulator of MAPK1 subtype 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; HRIHFB2063; KIAA2038; protein FAM59B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150946

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q75VX8

Gene Symbols:
GAREM2

Immunogen:
Recombinant Human FAM59B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG