PIPA569892

NUDT16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA569892-Each-of-1 In Stock ₹ 44,705.10

PIPA569892 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NUDT16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUDT16

Gene Alias

2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

75686

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q6P3D0

Gene Symbols

NUDT16

Immunogen

synthetic peptide directed towards the middle region of human NUDT16

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93% RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner
  • Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA
  • Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA
  • Catalyzes also the cleavage of the cap structure on mRNAs
  • Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG)
  • Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies
  • Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species
  • Binds to the U8 snoRNA; metal is not required for RNA-binding
  • May play a role in the regulation of snoRNAs and mRNAs degradation
  • Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms (PubMed:20385596, PubMed:26121039)
  • The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP (PubMed:20385596)
  • Binds strongly to GTP, ITP and XTP
  • Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (PubMed:20385596)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA569892

--


Antigen:
NUDT16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT16

Gene Alias:
2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
75686

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q6P3D0

Gene Symbols:
NUDT16

Immunogen:
synthetic peptide directed towards the middle region of human NUDT16

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA569893

--


Antigen:
C5orf24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C5orf24

Gene Alias:
C5orf24; chromosome 5 open reading frame 24; UPF0461 protein; UPF0461 protein C5orf24

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
134553

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q7Z6I8

Gene Symbols:
C5orf24

Immunogen:
synthetic peptide directed towards the middle region of human C5orf24

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA569899

--


Antigen:
PROCA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PROCA1

Gene Alias:
4933404M19Rik; PROCA1; proline-rich cyclin A1-interacting protein; protein interacting with cyclin A1; Protein PROCA1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147011

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
Q8NCQ7

Gene Symbols:
PROCA1

Immunogen:
synthetic peptide directed towards the middle region of human PROCA1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA569900

--


Antigen:
Xxylt1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XXYLT1

Gene Alias:
AI480653; C1H3orf21; C3orf21; im:6912235; LOW QUALITY PROTEIN: xyloside xylosyltransferase 1; PSEC0251; RGD1308154; si:dkey-25g11.2; UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase; uncharacterized protein C3orf21 homolog; XXYLT1; Xyloside xylosyltransferase 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
363799

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
XXYLT1

Immunogen:
synthetic peptide directed towards the C-terminal region of rat Xxylt1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG