PIPA572379
Phospho-TSC1 (Ser1141) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA572379-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA572379 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-TSC1 (Ser1141)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
60445
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Dot Blot
Concentration
0.28 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q9Z136
Gene Symbols
TSC1
Immunogen
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
Show Difference
Antigen: Phospho-TSC1 (Ser1141)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 60445
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot
Concentration: 0.28 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9Z136
Gene Symbols: TSC1
Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC1 (Ser1141)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
60445
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Dot Blot
Concentration:
0.28 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9Z136
Gene Symbols:
TSC1
Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TSC1 (Ser312)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 60445
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9Z136
Gene Symbols: TSC1
Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC1 (Ser312)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
60445
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Dot Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9Z136
Gene Symbols:
TSC1
Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TSC1 (Thr417)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 60445
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot
Concentration: 0.43 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9Z136
Gene Symbols: TSC1
Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T417 of rat TSC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC1 (Thr417)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
60445
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Dot Blot
Concentration:
0.43 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9Z136
Gene Symbols:
TSC1
Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T417 of rat TSC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TSC1 (Tyr297)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 60445
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Dot Blot
Concentration: 0.37 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9Z136
Gene Symbols: TSC1
Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y297 of rat TSC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC1 (Tyr297)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
60445
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Dot Blot
Concentration:
0.37 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9Z136
Gene Symbols:
TSC1
Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y297 of rat TSC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG