PIPA572807

IFIT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572807-Each-of-1 In Stock ₹ 44,705.10

PIPA572807 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IFIT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFIT3

Gene Alias

cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; P49; P60; retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3437

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O14879

Gene Symbols

IFIT3

Immunogen

IFIT3 antibody for an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is within amino acids 380 - 430 of IFIT3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication
  • Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription
  • Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27
  • Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation
  • IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels
  • Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21
  • Can negatively regulate the apoptotic effects of IFIT2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA572807

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; P49; P60; retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3437

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14879

Gene Symbols:
IFIT3

Immunogen:
IFIT3 antibody for an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is within amino acids 380 - 430 of IFIT3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572808

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Antigen:
DCANP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCANP1

Gene Alias:
C5orf20; DCANP1; DCNP1; dendritic cell associated nuclear protein; dendritic cell nuclear protein 1; Dendritic cell nuclear protein-1; dendritic cell-associated nuclear protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140947

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8TF63

Gene Symbols:
DCANP1

Immunogen:
DCNP1 antibody for an 18 amino acid peptide near the amino terminus of human DCNP1. The immunogen is within the first 50 amino acids of DCNP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572809

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Antigen:
OASL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OASL

Gene Alias:
2',5'-oligoadenylate synthetase-like 9; 2,5-oligoadenylate synthetase-like 9; 2'-5' oligoadenylate synthetase-like 1; 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 2'-5'-oligoadenylate synthase-like protein; 2'-5'-oligoadenylate synthase-like protein 1; 2'-5'-oligoadenylate synthetase like; 2'-5'-oligoadenylate synthetase-like; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; 7530414C13Rik; OASL; Oasl1; oasl9; OASLd; p59 OASL; p59OASL; p59-OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP14; TRIP-14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
231655, 304545, 8638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
G3V645, Q15646, Q8VI94

Gene Symbols:
OASL, Oasl1

Immunogen:
OASL antibody for a 17 amino acid peptide near the amino terminus of human OASL. The immunogen is within the first 50 amino acids of OASL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572810

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Antigen:
MIB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MIB1

Gene Alias:
DAPK-interacting protein 1; DAPK-interacting protein-1; DIP1; DIP-1; E3 ubiquitin-protein ligase MIB1; E430019M12Rik; KIAA1323; LVNC7; MIB; MIB1; Mind bomb homolog 1; mind bomb-1; mindbomb E3 ubiquitin protein ligase 1; mindbomb homolog 1; mindbomb homolog 1 (Drosophila); mKIAA1323; RING-type E3 ubiquitin transferase MIB1; skeletrophin; ubiquitin ligase mind bomb; zinc finger ZZ type with ankyrin repeat domain protein 2; ZZANK2; ZZZ6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225164, 307594, 57534

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80SY4, Q86YT6

Gene Symbols:
MIB1

Immunogen:
MIB1 antibody for a 19 amino acid peptide near the carboxy terminus of human MIB1. The immunogen is within amino acids 920 - 970 of MIB1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG