PIPA520508

IRGM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520508-Each-of-1 In Stock ₹ 47,785.26

PIPA520508 - Each of 1

₹ 47,785.26

In Stock

Quantity

1

Base Price: ₹ 47,785.26

GST (18%): ₹ 8,601.347

Total Price: ₹ 56,386.607

Antigen

IRGM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRGM

Gene Alias

Ifggd3; Ifi1; Iigp3; Iipg3; immunity related GTPase M; immunity related GTPase m1; immunity-related GTPase family M member 1; immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1; immunity-related GTPase family, M; immunity-related GTPase family, M1; immunity-related GTPase M; interferon inducible protein 1; interferon-gamma-inducible GTPase Ifggd3 protein; interferon-inducible GTPase 3; Interferon-inducible protein 1; Irgm; Irgm1; LPS-stimulated RAW 264.7 macrophage protein 47; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG 47; LRG47; LRG-47; LRG-47-like protein; MGC149263

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15944, 303090, 345611

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

A1A4Y4, Q60766, Q6AYC2

Gene Symbols

IRGM, Irgm1

Immunogen

A 14 amino acid peptide near the center of the human IRGM.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human brain tissue lysate
  • PA5-20508 can be used with blocking peptide PEP-0628
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • Two of the strongest hits implicate genes IRGM and ATG16L1, which encode proteins thought to be critical to the autophagy pathway and being significantly associated with Crohn's disease
  • In mouse, IRGM belongs to a family of -gamma-interferon-induced GTP-binding proteins of approximately 48 kDa
  • Murine IRGM induces autophagy and generates large autolysosomal organelles as a mechanism for the elimination of intracellular Mycobacterium tuberculosis
  • Human IRGM is also involved in autophagy and plays a role in the control of intracellular pathogens and in the reduction of intracellular bacillary load.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520508

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Antigen:
IRGM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRGM

Gene Alias:
Ifggd3; Ifi1; Iigp3; Iipg3; immunity related GTPase M; immunity related GTPase m1; immunity-related GTPase family M member 1; immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1; immunity-related GTPase family, M; immunity-related GTPase family, M1; immunity-related GTPase M; interferon inducible protein 1; interferon-gamma-inducible GTPase Ifggd3 protein; interferon-inducible GTPase 3; Interferon-inducible protein 1; Irgm; Irgm1; LPS-stimulated RAW 264.7 macrophage protein 47; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG 47; LRG47; LRG-47; LRG-47-like protein; MGC149263

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15944, 303090, 345611

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A1A4Y4, Q60766, Q6AYC2

Gene Symbols:
IRGM, Irgm1

Immunogen:
A 14 amino acid peptide near the center of the human IRGM.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520509

--


Antigen:
UNC93A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UNC93A

Gene Alias:
dJ366N23.1; dJ366N23.1 (putative C. elegans UNC-93 (protein 1, C46F11.1) LIKE); dJ366N23.2; dJ366N23.2 (putative C. elegans UNC-93 (protein 1, C46F11.1) C-terminal LIKE); HmUnc-93A; Protein unc-93 homolog A; unc93 homolog A; unc-93 homolog A (C. elegans); UNC93A; Unc-93A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54346

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q86WB7

Gene Symbols:
UNC93A

Immunogen:
An 18 amino acid peptide from near the carboxy terminus of human Unc93a.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520510

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Antigen:
UNC93B1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UNC93B1

Gene Alias:
hUNC93B1; IIAE1; Protein unc-93 homolog B1; UNC93; unc93 homolog B; unc-93 homolog B; unc93 homolog B1; unc-93 homolog B1 (C. elegans); unc-93 related protein; UNC93B; Unc93b1; Unc-93B1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361689, 54445, 81622

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8VCW4, Q9H1C4

Gene Symbols:
UNC93B1

Immunogen:
A 19 amino acid peptide from near the amino terminus of human Unc93b.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520511

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Antigen:
AMBRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBRA1

Gene Alias:
2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228361, 55626, 59319

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A2AH22, Q9C0C7

Gene Symbols:
AMBRA1

Immunogen:
A 15 amino acid peptide from near the carboxy terminus of human Ambra1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG