PIPA520663

EBI3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520663-Each-of-1 In Stock ₹ 44,277.30

PIPA520663 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

EBI3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EBI3

Gene Alias

cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10148, 50498, 680609

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O35228, Q14213

Gene Symbols

EBI3

Immunogen

A 16 amino acid peptide from near the center of human EBI3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA520281

--

Img

Thermo Scientific

PIPA520398

--

Img

Thermo Scientific

PIPA520497

--

Img

Thermo Scientific

PIPA582165

--

Img

Thermo Scientific

PIPA572807

--

Img

Thermo Scientific

PIPA520547

--

Img

Thermo Scientific

PIPA520508

--

Img

Thermo Scientific

PIPA554286

--

Description

  • A suggested positive control is rat spleen tissue lysate
  • PA5-20663 can be used with blocking peptide PEP-0783
  • EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family
  • It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function
  • EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively
  • IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation
  • It negatively regulates Th17 cell differentiation
  • EBI3 is widely expressed and its expression in dendritic cell is transcriptionally regulated by TLR signaling via MyD88 and NF-kappaB during innate immune responses preceding cytokine driven Th cell development
  • EBI3 signal inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction
  • EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma
  • Targeted deletion of EBI3 protects mice from lung metastasis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520663

--


Antigen:
EBI3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EBI3

Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10148, 50498, 680609

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O35228, Q14213

Gene Symbols:
EBI3

Immunogen:
A 16 amino acid peptide from near the center of human EBI3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520665

--


Antigen:
TREX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX1

Gene Alias:
1661; 3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; AU041952; CRV; Deoxyribonuclease III; DNase III; DRN3; HERNS; RGD1309596; three prime exonuclease 1; three prime repair exonuclease 1; three-prime repair exonuclease 1; Trex1; trophoblast expressed 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100049583, 11277, 22040

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q91XB0, Q9NSU2

Gene Symbols:
TREX1

Immunogen:
A 15 amino acid peptide near the center of human TREX1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520666

--


Antigen:
TREX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX2

Gene Alias:
3'-5' exonuclease TREX2; 3'-5' exonuclease TREX2 long form; RGD1562245; Three prime repair exonuclease 2; Trex2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11219, 24102, 309275

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9BQ50, Q9R1A9

Gene Symbols:
TREX2

Immunogen:
A 15 amino acid peptide near the carboxy terminus of human TREX2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520670

--


Antigen:
IL-16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL16

Gene Alias:
FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116996, 16170, 3603

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O54824, Q14005

Gene Symbols:
IL16

Immunogen:
A 20 amino acid peptide near the amino terminus of human IL-16.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG