PIPA572904

DEDD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572904-Each-of-1 In Stock ₹ 44,705.10

PIPA572904 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DEDD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dedd2

Gene Alias

2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.02% sodium azide

Gene Accession No.

Q8WXF8

Gene Symbols

Dedd2

Immunogen

A synthetic peptide corresponding to amino acids 210-228 of human DEDD2/Flame-3 was used as immunogen; GenBank no. gi 19923050 ref NP_579874.1.

Regulatory Status

RUO

Gene ID (Entrez)

162989, 534251, 613012, 687118

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain
  • A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified
  • Over-expression of DEDD2 in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD
  • More recently, it has been shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD
  • Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis
  • At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA572904

--


Antigen:
DEDD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dedd2

Gene Alias:
2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q8WXF8

Gene Symbols:
Dedd2

Immunogen:
A synthetic peptide corresponding to amino acids 210-228 of human DEDD2/Flame-3 was used as immunogen; GenBank no. gi 19923050 ref NP_579874.1.

Regulatory Status:
RUO

Gene ID (Entrez):
162989, 534251, 613012, 687118

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572905

--


Antigen:
DEDD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dedd2

Gene Alias:
2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q8WXF8

Gene Symbols:
Dedd2

Immunogen:
A synthetic peptide corresponding to amino acids 175-193 of human DEDD2/Flame-3 was used as immunogen; GenBank no. gi 19923050 ref NP_579874.1

Regulatory Status:
RUO

Gene ID (Entrez):
162989

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572906

--


Antigen:
PTPN13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN13

Gene Alias:
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q12923

Gene Symbols:
PTPN13

Immunogen:
A recombinant protein corresponding to amino acids 1279 to 1883 of human FAP-1 protein was used as immunogen; GenBank no. NP_542414.1.

Regulatory Status:
RUO

Gene ID (Entrez):
5783

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA572907

--


Antigen:
PTPN13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN13

Gene Alias:
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q12923

Gene Symbols:
PTPN13

Immunogen:
A synthetic peptide corresponding to amino acids 1760-1775 of human FAP-1; GenBank no. NP_542414.1. This peptide sequence is conserved in multiple isoforms of FAP-1.

Regulatory Status:
RUO

Gene ID (Entrez):
5783

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid