PIPA572913

RIP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572913-Each-of-1 In Stock ₹ 44,705.10

PIPA572913 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RIP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RIPK1

Gene Alias

cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.05% sodium azide

Gene Accession No.

Q13546

Gene Symbols

RIPK1

Immunogen

A synthetic peptide corresponding to amino acids 269-287 of human RIP1 was used as immunogen, GenBank no. AAC32232.1.

Regulatory Status

RUO

Gene ID (Entrez)

8737

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage
  • Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor
  • Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade
  • Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules
  • Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation
  • Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death
  • RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA572913

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Antigen:
RIP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q13546

Gene Symbols:
RIPK1

Immunogen:
A synthetic peptide corresponding to amino acids 269-287 of human RIP1 was used as immunogen, GenBank no. AAC32232.1.

Regulatory Status:
RUO

Gene ID (Entrez):
8737

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572915

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Antigen:
SEMG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEMG1

Gene Alias:
Alpha-inhibin-31; Alpha-inhibin-92; BB115391; Cancer/testis antigen 103; CT103; dJ172H20.2; MGC14719; RATSVPIIA; semen coagulating protein; semenoclotin; semenogelin I; Semenogelin-1; SEMG; SEMG1; Seminal basic protein; seminal vesicle protein, secretion 1; seminal vesicle protein, secretion 2; seminal vesicle secretory protein 2; seminal vesicle secretory protein II; SGI; SgI-29; Svp1; Svp-1; Svp5; SVPIIA; SVS II; Svs2; SVS2P; Svs2p2; Svs5; SvsII

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Gerbil, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P04279

Gene Symbols:
SEMG1, Svs2

Immunogen:
Gel purified rat p47 seminal vesicle protein I (secreted Semenogelin I) from rodent seminal vesicle secretion fluid was used as immunogen.

Regulatory Status:
RUO

Gene ID (Entrez):
25013, 53878, 6406

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572916

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Antigen:
TRAF-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF1

Gene Alias:
4732496E14Rik; EBI6; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; TNF receptor associated factor 1; TNF receptor-associated factor 1; Traf1

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P39428

Gene Symbols:
TRAF1

Immunogen:
A synthetic peptide corresponding to amino acids 51-69 of mouse TRAF1 was used as immunogen, GenBank no. NP_033447.2.

Regulatory Status:
RUO

Gene ID (Entrez):
22029

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572917

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Antigen:
TRAF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF4

Gene Alias:
A530032M13Rik; Cart1; cysteine-rich domain associated with ring and TRAF domain; cysteine-rich domain associated with RING and Traf domains protein 1; Cysteine-rich motif associated to RING and Traf domains protein 1; malignant 62; metastatic lymph node gene 62 protein; MLN 62; MLN62; msp2; RING finger protein 83; RNF83; RNF83malignant 62; TNF receptor associated factor 4; TNF receptor-associated factor 4; tnf receptor-associated factor 4b; traf4; TRAF4 protein; TRAF4 variant 6; traf4b; tumor necrosis receptor-associated factor 4A

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q61382, Q9BUZ4

Gene Symbols:
TRAF4, traf4b

Immunogen:
A synthetic peptide corresponding to amino acids 1-17 of human TRAF4 was used as immunogen; GenBank no. gi 22027622 ref NP_004286.2.

Regulatory Status:
RUO

Gene ID (Entrez):
22032, 303285, 404035, 781568, 9618

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid