PIPA573010

DNMT3L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA573010-Each-of-1 In Stock ₹ 44,705.10

PIPA573010 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DNMT3L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNMT3L

Gene Alias

cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

29947

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

Q9UJW3

Gene Symbols

DNMT3L

Immunogen

A portion of amino acids 25-75 from human Dnmt3L was used as the immunogen for this antibody.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

Description

  • Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and development
  • Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2, and DNMT3
  • DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication
  • DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues
  • DNMT3A and DNMT3B function as de novo methyltransferases that methylate previously unmethylated regions of DNA
  • DNMT2 is expressed at low levels in adult somatic tissues and its inactivation affects neither de novo nor maintenance DNA methylation
  • DNMT3L is a catalytically inactive regulatory factor for the DNMT3A and DNMT3B de novo methyltransferases that is expressed at low levels in embryonic stem cells, testis, ovaries, and thymus
  • These de novo methyltransferases consist of a heterotetrameric complex containing two molecules of DNMT3L, and either two molecules of DNMT3A or DNMT3B
  • DNMT3L contains an amino-terminal ATRX-DNMT3-DNMT3L (ADD) domain and a carboxy-terminal methyltransferase-like domain.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA573010

--


Antigen:
DNMT3L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNMT3L

Gene Alias:
cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29947

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q9UJW3

Gene Symbols:
DNMT3L

Immunogen:
A portion of amino acids 25-75 from human Dnmt3L was used as the immunogen for this antibody.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573013

--


Antigen:
AP3D1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ap3d1

Gene Alias:
AA407035; adapter-related protein complex 3 subunit delta-1; adaptin, delta; adaptor related protein complex 3 delta 1 subunit; adaptor related protein complex 3 subunit delta 1; adaptor related protein complex 3, delta 1 subunit; adaptor-related protein complex 3 subunit delta-1; adaptor-related protein complex 3, delta 1 subunit; adaptor-related protein complex 3, delta subunit; adaptor-related protein complex AP-3, delta subunit; ADTD; ap3; AP-3 complex delta subunit, partial CDS; AP-3 complex subunit delta; AP-3 complex subunit delta-1; Ap3d; Ap3d1; Bolvr; delta adaptin; delta-adaptin; delta-adaptin, partial CDS; hBLVR; mBLVR1; mh; mocha; PRO0039; subunit of putative vesicle coat adaptor complex AP-3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O14617

Gene Symbols:
Ap3d1

Immunogen:
A portion of amino acids 530-580 of human AP3 Delta was used as the immunogen for the antibody.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573014

--


Antigen:
C6orf57

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SDHAF4

Gene Alias:
1110058L19Rik; 1700001E18Rik; C6orf57; hypothetical protein LOC685888; LOC685888; SDH assembly factor 4; Sdh8; SDHAF4; Succinate dehydrogenase assembly factor 4, mitochondrial; succinate dehydrogenase complex assembly factor 4; UPF0369 protein C6orf57; UPF0369 protein C6orf57 homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
68002

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q8BTE0

Gene Symbols:
SDHAF4

Immunogen:
A portion of amino acids 75-129 of mouse UPF0369 protein C6orf57 homolog was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573016

--


Antigen:
SHARPIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
475122, 81858

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
A portion of amino acids 25-75 of human Sharpin was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG