PIPA573016

SHARPIN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA573016-Each-of-1 In Stock ₹ 44,705.10

PIPA573016 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SHARPIN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

475122, 81858

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

Q9H0F6

Gene Symbols

SHARPIN

Immunogen

A portion of amino acids 25-75 of human Sharpin was used as the immunogen.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG

Description

  • Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

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Img

Thermo Scientific

PIPA573016

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Antigen:
SHARPIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
475122, 81858

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
A portion of amino acids 25-75 of human Sharpin was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573019

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Antigen:
VPRBP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCAF1

Gene Alias:
AI447437; B930007L02Rik; DCAF1; DDB1 and CUL4 associated factor 1; DDB1- and CUL4-associated factor 1; HIV-1 Vpr binding protein; HIV-1 Vpr-binding protein; KIAA0800; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 1; MGC102804; mKIAA0800; Protein VPRBP; protein VPRBP; DDB1- and CUL4-associated factor 1; RGD1305176; RIP; Serine/threonine-protein kinase VPRBP; Vpr (HIV-1) binding protein; Vpr-binding protein; VprBP; vpr-interacting protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100061218, 100343053, 100519566, 100734659, 100768333, 101097051, 315987, 321006, 415921, 9730

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q80TR8, Q9Y4B6

Gene Symbols:
DCAF1

Immunogen:
A portion of amino acids 935-985 from human VPRBP was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Equine, Feline, Guinea Pig, Hamster, Human, Marsupial, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573022

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Antigen:
SAMHD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SAMHD1

Gene Alias:
CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; E330031J07Rik; EGK_02438; HDDC1; hSAMHD1; IFN-gamma induced; interferon-gamma-inducible protein Mg11; Mg11; Mg21; Monocyte protein 5; MOP5; MOP-5; mSAMHD1; RP1-132F21.1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1; SAM domain and HD domain 1; SAM domain and HD domain, 1; SAM domain and HD domain-containing protein 1; Samhd1; SBBI88

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25939, 311580, 56045

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q60710, Q9Y3Z3

Gene Symbols:
SAMHD1

Immunogen:
This antibody was raised against SAMHD1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA573023

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Antigen:
HES7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HES7

Gene Alias:
bHLH factor Hes7; bHLHb37; class B basic helix-loop-helix protein 37; Hairy and enhancer of split 7; hairy and enhancer of split 7 (Drosophila); hes family bHLH transcription factor 7; HES7; hHes7; mHes7; SCDO4; transcription factor HES-7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287423, 84653, 84667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
antibody with no preservative

Gene Accession No.:
Q8BKT2, Q9BYE0

Gene Symbols:
HES7

Immunogen:
Antibody for amino acid sequence 6-23 (RAENRDGPkMLkPLVEkRc) was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG