PIPA575703

TNP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575703-Each-of-1 In Stock ₹ 44,705.10

PIPA575703 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TNP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNP2

Gene Alias

haploid expressed, male germcell specific, chromatin binding; nuclear transition protein 2; TNP2; TP2; TP-2; transition protein 2; transition protein 2 (during histone to protamine replacement)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24840, 7142

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P11101, Q05952

Gene Symbols

TNP2

Immunogen

Synthetic peptide corresponding to residues in Human TNP2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • During mammalian spermiogenesis, histones are transiently replaced by several low molecular weight proteins called transition proteins (TNPs)
  • Transition proteins facilitate chromatin transformation from the nucleosome structure to the nucleoprotamine structure during spermatid differentiation
  • Transition protein-2, also known as TNP2, and TP2, maps to human chromosome 16p13.13 and encodes a highly basic nuclear protein
  • TNP2 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines
  • TNP2 is not a critical factor for shaping of the sperm nucleus, histone displacement, initiation of chromatin condensation, binding of protamines to DNA, or fertility
  • However, TNP2 is necessary for maintaining the normal processing of protamine 2 and, consequently, the completion of chromatin condensation
  • If TNP1 is missing, TNP2 may partially compensate for TNP1, but this dysregulation of nucleoprotein replacement results in an abnormal pattern of chromatin condensation and in reduced fertility .

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Img

Thermo Scientific

PIPA575703

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Antigen:
TNP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNP2

Gene Alias:
haploid expressed, male germcell specific, chromatin binding; nuclear transition protein 2; TNP2; TP2; TP-2; transition protein 2; transition protein 2 (during histone to protamine replacement)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24840, 7142

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P11101, Q05952

Gene Symbols:
TNP2

Immunogen:
Synthetic peptide corresponding to residues in Human TNP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575704

--


Antigen:
MCFD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mcfd2

Gene Alias:
1810021C21Rik; F5F8D; F5F8D2; LMAN1IP; MCFD2; multiple coagulation factor deficiency 2; multiple coagulation factor deficiency protein 2; Multiple coagulation factor deficiency protein 2 homolog; neural stem cell derived neuronal survival protein; neural stem cell-derived neuronal survival protein; Sdnsf; stem cell derived neuronal survival protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
246117, 90411

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8K5B3, Q8NI22

Gene Symbols:
Mcfd2

Immunogen:
Synthetic peptide corresponding to residues in Human MCFD2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA575706

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Antigen:
FUNDC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FUNDC1

Gene Alias:
1500005J14Rik; 1810033P05Rik; FUN14 domain containing 1; FUN14 domain-containing protein 1; fundc1; hypothetical protein LOC436984; si:ch211-222m21.2; zgc:92600

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
139341, 363442, 72018

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5BJS4, Q8IVP5, Q9DB70

Gene Symbols:
FUNDC1

Immunogen:
Synthetic peptide corresponding to residues in Human FUNDC1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA575707

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Antigen:
CST9LP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CST9LP1

Gene Alias:
CST9LP1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
128820

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5W188

Gene Symbols:
CST9LP1

Immunogen:
Synthetic peptide corresponding to residues in Human CST9LP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG