PIPA577020

TNP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA577020-Each-of-1 In Stock ₹ 47,614.14

PIPA577020 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

TNP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNP2

Gene Alias

haploid expressed, male germcell specific, chromatin binding; nuclear transition protein 2; TNP2; TP2; TP-2; transition protein 2; transition protein 2 (during histone to protamine replacement)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7142

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q05952

Gene Symbols

TNP2

Immunogen

Recombinant full length Human TNP2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • During mammalian spermiogenesis, histones are transiently replaced by several low molecular weight proteins called transition proteins (TNPs)
  • Transition proteins facilitate chromatin transformation from the nucleosome structure to the nucleoprotamine structure during spermatid differentiation
  • Transition protein-2, also known as TNP2, and TP2, maps to human chromosome 16p13.13 and encodes a highly basic nuclear protein
  • TNP2 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines
  • TNP2 is not a critical factor for shaping of the sperm nucleus, histone displacement, initiation of chromatin condensation, binding of protamines to DNA, or fertility
  • However, TNP2 is necessary for maintaining the normal processing of protamine 2 and, consequently, the completion of chromatin condensation
  • If TNP1 is missing, TNP2 may partially compensate for TNP1, but this dysregulation of nucleoprotein replacement results in an abnormal pattern of chromatin condensation and in reduced fertility .

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Thermo Scientific

PIPA577020

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Antigen:
TNP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNP2

Gene Alias:
haploid expressed, male germcell specific, chromatin binding; nuclear transition protein 2; TNP2; TP2; TP-2; transition protein 2; transition protein 2 (during histone to protamine replacement)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7142

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q05952

Gene Symbols:
TNP2

Immunogen:
Recombinant full length Human TNP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA577021

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Antigen:
TRAPPC10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAPPC10

Gene Alias:
B230307C21Rik; EHOC1; EHOC-1; epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Gm870; GT334; Protein GT334; TMEM1; trafficking protein particle complex 10; trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 10; LOW QUALITY PROTEIN: trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; trafficking protein particle complex subunit TMEM1; transmembrane protein 1; transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1; trappc10; TRS130; TRS30; wu:fc21a02

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
216131, 309678, 7109

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P48553, Q3TLI0

Gene Symbols:
TRAPPC10

Immunogen:
Recombinant full length Human TRAPPC10.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA577024

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Antigen:
DCAF7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCAF7

Gene Alias:
1700012F10Rik; 2610037L01Rik; AN11; AN11 homolog; C86529; DCAF7; DDB1 and CUL4 associated factor 7; DDB1- and CUL4-associated factor 7; dirty south; dys; fj83g06; HAN11; han11l; human anthocyanin; RGD1305140; seven-WD-repeat protein of the AN11 family-1; SWAN-1; Unknown (protein for MGC:134591); WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; wdr68; WD-repeat protein; wu:fj83g06; zgc:63940

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10238, 71833

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P61962, P61963

Gene Symbols:
DCAF7

Immunogen:
Recombinant full length Human DCAF7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA577026

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Antigen:
hnRNP D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HNRNPD

Gene Alias:
ARE-binding protein AUFI, type A; Auf1; AUF1A; AU-rich element RNA binding protein 1, 37kDa; AU-rich element RNA-binding factor 1; AU-rich element RNA-binding protein 1; heterogeneous nuclear ribonucleoprotein D; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; HNRNPD; hnRNPD0; Hnrpd; P37; RNA binding protein p45AUF1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11991, 3184, 79256

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14103, Q60668, Q9JJ54

Gene Symbols:
HNRNPD

Immunogen:
Recombinant full length Human hnRNP D.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG