PIPA575743

GFI1B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575743-Each-of-1 In Stock ₹ 44,705.10

PIPA575743 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GFI1B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GFI1B

Gene Alias

BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14582, 311832, 8328

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O70237, Q5VTD9

Gene Symbols

GFI1B

Immunogen

Synthetic peptide corresponding to residues in Human GFI1B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • GFI1b (zinc finger protein GFI-1b) is an essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages
  • It is also a component of a RCOR-GFI-KDM1A-HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation
  • GFI1b also acts as a transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine signaling pathways
  • It also cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate
  • Mutations affecting the gene are associated with Bleeding disorder, platelet-type 17 (BDPLT17).

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA575743

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Antigen:
GFI1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GFI1B

Gene Alias:
BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14582, 311832, 8328

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O70237, Q5VTD9

Gene Symbols:
GFI1B

Immunogen:
Synthetic peptide corresponding to residues in Human GFI1B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575744

--


Antigen:
HOXC10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HOXC10

Gene Alias:
AI506621; homeo box C10; homeobox C10; homeobox protein Hox-3.6; Homeobox protein Hox-3I; homeobox protein Hox-C10; homeoprotein C10; Hox3.5 homeobox; Hox-3.6; HOX3I; HOXC10; Hoxc-10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
209448, 315338, 3226

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P31257, Q9NYD6

Gene Symbols:
HOXC10

Immunogen:
Synthetic peptide corresponding to residues in Human HOXC10

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA575745

--


Antigen:
ABHD13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABHD13

Gene Alias:
1110065L07Rik; Abhd13; abhydrolase domain containing 13; abhydrolase domain-containing protein 13; AI463703; AI788994; Alpha/beta hydrolase domain-containing protein 13; bA153I24.2; BEM46L1; C13orf6; Protein ABHD13; RGD1308317; RP11-153I24.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
306630, 68904, 84945

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q7L211, Q80UX8

Gene Symbols:
ABHD13

Immunogen:
Synthetic peptide corresponding to residues in Human ABHD13

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA575747

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Antigen:
RTDR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RSPH14

Gene Alias:
4933431K05Rik; MGC16968; Radial spoke head 14 homolog; radial spoke head homolog 14 (Chlamydomonas); rhabdoid tumor deletion region gene 1; rhabdoid tumor deletion region protein 1; Rsph14; Rtdr1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27156, 365552, 71236

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9D3W1, Q9UHP6

Gene Symbols:
RSPH14

Immunogen:
Synthetic peptide corresponding to residues in Human RTDR1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG